Evaluation of bicuspid aortic valve-associated aortopathic changes using third-generation dual-source computed tomography

doi:10.4329/wjr.120056

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World Journal of Radiology

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1949-8470

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Radiol. Jun 28, 2026; 18(6): 120056
Published online Jun 28, 2026. doi: 10.4329/wjr.120056

Table 3 Receiver operating characteristic characteristics of aortic size index and comparison with imaging modalities

Parameter	Value (95%CI)
ROC analysis for predicting aortic dilatation > 40 mm
ASI (cutoff ≥ 23.8 mm/m²)
AUROC	0.935 (0.891-0.979)
Sensitivity (%)	84 (72-92)
Specificity (%)	90 (76-97)
Positive predictive value (%)	92.7 (82-98)
Negative predictive value (%)	77.8 (63-89)
Diagnostic accuracy (%)	86 (78-92)
CT ascending aorta diameter (cutoff ≥ 40 mm)
AUROC	0.972 (0.942-1.000)
Sensitivity (%)	100 (94-100)
Specificity (%)	90 (76-97)
Diagnostic accuracy (%)	96 (90-99)
Echocardiography diameter (cutoff ≥ 34 mm)
AUROC	0.773 (0.633-0.912)
Sensitivity (%)	68 (48-84)
Specificity (%)	90 (67-99)
Diagnostic accuracy (%)	76.6 (62-88)
CT vs echocardiography agreement
Mean diameter difference (mm)	11.72 ± 8.27
Weighted Kappa coefficient	0.356 (fair agreement)

ROC: Receiver operating characteristic; ASI: Aortic size index; AUROC: Area under receiver operating characteristic curve; CT: Computed tomography.

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Citation: Thanihaivel E S, Sharma A, Verma M, Vijayvergiya R, Singhal M. Evaluation of bicuspid aortic valve-associated aortopathic changes using third-generation dual-source computed tomography. World J Radiol 2026; 18(6): 120056
URL: https://www.wjgnet.com/1949-8470/full/v18/i6/120056.htm
DOI: https://dx.doi.org/10.4329/wjr.120056

Thanihaivel E S, Sharma A, Verma M, Vijayvergiya R, Singhal M. Evaluation of bicuspid aortic valve-associated aortopathic changes using third-generation dual-source computed tomography. World J Radiol 2026; 18(6): 120056 [PMID: 42395106 DOI: 10.4329/wjr.120056]

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