Predictive performance of cervical elastography for preterm birth: A head-to-head network meta-analysis

Table 2 Combined area under the curve, sensitivity, specificity, and diagnostic odds ratio for E-cervix parameters and conventional measurement parameters

Parameters	AUC (95%CrI)	Sensitivity (95%CrI)	Specificity (95%CrI)	DOR (95%CrI)	LR+ (95%CrI)	LR- (95%CrI)	S	RR_Se vs CL	RR_Sp vs CL
CL	0.70 (0.60-0.77)	0.63 (0.54-0.71)	0.67 (0.57-0.76)	3.58 (1.91-6.25)	1.89 (1.24-2.90)	0.56 (0.39-0.82)	0.28 (0.08-1.00)	1.00 (1.00-1.00)	1.00 (1.00-1.00)
ACA	0.86 (0.71-0.93)	0.78 (0.65-0.89)	0.75 (0.58-0.87)	13.65 (3.88-35.20)	3.15 (1.55-7.04)	0.29 (0.13-0.61)	5.70 (0.33-15.00)	1.25 (1.01-1.53)	1.13 (0.86-1.40)
IOS	0.76 (0.65-0.83)	0.56 (0.45-0.67)	0.80 (0.70-0.87)	5.47 (2.59-10.06)	2.75 (1.50-5.13)	0.55 (0.38-0.78)	0.73 (0.14-3.00)	0.90 (0.71-1.10)	1.20 (1.01-1.44)
EOS	0.72 (0.68-0.76)	0.57 (0.51-0.64)	0.78 (0.75-0.81)	4.00 (2.81-5.69)	2.27 (1.65-3.12)	0.61 (0.50-0.75)	0.58 (0.08-2.33)	1.07 (0.86-1.29)	0.98 (0.75-1.24)
IOS/EOS ratio	0.72 (0.58-0.80)	0.68 (0.57-0.78)	0.63 (0.49-0.75)	4.05 (1.64-8.14)	1.84 (1.10-3.17)	0.50 (0.30-0.89)	0.46 (0.08-2.33)	1.09 (0.89-1.31)	0.95 (0.72-1.19)
ECI	0.73 (0.63-0.80)	0.67 (0.57-0.76)	0.67 (0.56-0.77)	4.52 (2.24-8.21)	2.04 (1.30-3.29)	0.49 (0.31-0.77)	0.60 (0.09-2.33)	1.08 (0.89-1.29)	1.01 (0.81-1.23)
HR	0.80 (0.72-0.85)	0.76 (0.68-0.82)	0.70 (0.60-0.78)	7.71 (4.06-13.06)	2.51 (1.69-3.75)	0.35 (0.23-0.54)	2.18 (0.20-9.00)	1.21 (1.04-1.41)	1.05 (0.87-1.28)
Combined	0.91 (0.83-0.95)	0.83 (0.74-0.89)	0.83 (0.73-0.90)	26.23 (10.47-54.64)	4.76 (2.70-8.74)	0.21 (0.12-0.36)	12.90 (3.67-15.00)	1.32 (1.13-1.55)	1.25 (1.04-1.48)

Heterogeneity was quantified using Cochran’s Q test and the I² statistic; a random-effects model was employed if I² > 50% or P < 0.10 for Cochran’s Q test, indicating significant heterogeneity; otherwise, a fixed-effects model was used. AUC: Area under the curve; CrI: Credible interval; DOR: Diagnostic odds ratios; LR: Likelihood ratios; S: Advantage index, a ranking metric for diagnostic performance; higher values indicate superior overall accuracy; RR_Se/RR_Sp vs CL: Relative ratio compared to cervical length (reference); CL: Cervical length; ACA: Anterior cervical angle; IOS: Internal os strain; EOS: External os strain; ECI: Elasticity contrast index; HR: Hardness ratio.