Functional connectivity alterations in patients with poststroke cognitive impairment: A resting-state functional magnetic resonance imaging study

doi:10.4329/wjr.v18.i2.116799

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World Journal of Radiology

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1949-8470

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World J Radiol. Feb 28, 2026; 18(2): 116799
Published online Feb 28, 2026. doi: 10.4329/wjr.v18.i2.116799

Table 3 Comparison of functional connectivity between the poststroke cognitive impairment group and the control group

Inter-regional FC	PSCI group	Control group	t value	P value
Cerebelum_4_5_R and Cerebelum_6_R	1.06 ± 0.26	0.58 ± 0.22	4.5326	0.0001
Cerebelum_4_5_R and Cerebelum_8_R	0.68 ± 0.25	0.29 ± 0.24	4.0434	0.0004
Amygdala_L and Cerebelum_9_L	0.37 ± 0.21	0.06 ± 0.26	3.8097	0.0007
Cerebelum_4_5_L and Cerebelum_9_L	0.65 ± 0.20	0.24 ± 0.25	4.1890	0.0002
Cerebelum_4_5_R and Cerebelum_9_L	0.65 ± 0.17	0.19 ± 0.26	4.7038	0.0001
Cerebelum_6_R and Cerebelum_9_L	0.73 ± 0.32	0.33 ± 0.23	3.6753	0.0010
Cerebelum_4_5_L and Cerebelum_9_R	0.61 ± 0.25	0.20 ± 0.28	3.8625	0.0006
Cerebelum_4_5_R and Cerebelum_9_R	0.68 ± 0.21	0.20 ± 0.30	4.0530	0.0003
Fusiform_R and Vermis_3	0.44 ± 0.26	0.17 ± 0.15	3.8251	0.0006
Cerebelum_4_5_R and Vermis_3	0.71 ± 0.23	0.35 ± 0.25	3.8691	0.0006
Cerebelum_6_R and Vermis_3	0.62 ± 0.28	0.24 ± 0.17	3.9236	0.0005
Cerebelum_8_R and Vermis_3	0.56 ± 0.17	0.08 ± 0.17	4.4017	0.0001
Cerebelum_9_L and Vermis_3	0.52 ± 0.17	0.08 ± 0.29	3.7043	0.0009
Cerebelum_9_R and Vermis_3	0.53 ± 0.16	0.06 ± 0.30	3.9206	0.0005
Cerebelum_10_L and Vermis_3	0.44 ± 0.26	0.01 ± 0.17	4.4302	0.0001
Cerebelum_4_5_R and Vermis_4_5	0.85 ± 0.22	0.54 ± 0.14	5.6876	0.0000
Cerebelum_4_5_R and Vermis_8	0.72 ± 0.33	0.16 ± 0.35	4.2980	0.0002
Cerebelum_4_5_L and Vermis_9	0.61 ± 0.29	0.17 ± 0.30	3.9113	0.0005
Cerebelum_4_5_R and Vermis_9	0.61 ± 0.33	0.13 ± 0.26	4.3557	0.0002
Cerebelum_6_R and Vermis_9	0.75 ± 0.36	0.36 ± 0.23	4.2176	0.0002

The two-sample t tests of the data from the two groups revealed a significant positive functional connectivity (t value significantly > 0; that is, the poststroke cognitive impairment group > the control group, and the inter-regional functional connectivity of the poststroke cognitive impairment group increased significantly in the following brain regions). FC: Functional connectivity; PSCI: Poststroke cognitive impairment.

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Citation: Tao YY, Wang R, Zhang P, Huang XH, Yang L. Functional connectivity alterations in patients with poststroke cognitive impairment: A resting-state functional magnetic resonance imaging study. World J Radiol 2026; 18(2): 116799
URL: https://www.wjgnet.com/1949-8470/full/v18/i2/116799.htm
DOI: https://dx.doi.org/10.4329/wjr.v18.i2.116799

Tao YY, Wang R, Zhang P, Huang XH, Yang L. Functional connectivity alterations in patients with poststroke cognitive impairment: A resting-state functional magnetic resonance imaging study. World J Radiol 2026; 18(2): 116799 [PMID: 41809709 DOI: 10.4329/wjr.v18.i2.116799]

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