Interpretable model based on multisequence magnetic resonance imaging radiomics for predicting the pathological grades of hepatocellular carcinomas

Table 4 Results of univariate and multivariate logistic regression analyses

Clinical factors	Univariate logistic regression analysis		Multivariate logistic regression analysis
	OR (95%CI)	P value	OR (95%CI)	P value
Age (years)	0.980 (0.934-1.028)	0.406	-	-
Sex	0.328 (0.071-1.510)	0.152	-	-
NLR	1.009 (0.935-1.088)	0.826	-	-
PLR	1.005 (0.997-1.012)	0.209	-	-
LMR	0.675 (0.439-1.039)	0.074	-	-
Maximum tumor diameter (cm)	1.232 (1.051-1.444)	0.0101	1.364 (1.065-1.746)	0.0141
Portal vein tumor thrombus	3.500 (0.972-12.597)	0.055	-	-
Lymph node metastasis	2.520 (0.661-9.603)	0.176	-	-
HBV	0.106 (0.029-0.391)	< 0.0011	0.120 (0.020-0.729)	0.0211
Liver cirrhosis	0.237 (0.072-0.787)	0.0191	0.326 (0.053-2.020)	0.228
AFP (ng/mL)	1.067 (0.323-3.525)	0.916	-	-
PLT (109/L)	1.007 (1.001-1.014)	0.0351	0.994 (0.984-1.005)	0.296
LYMPH (109/L)	1.364 (0.614-3.030)	0.446	-	-
NEU (109/L)	1.140 (0.981-1.325)	0.088	-	-
MONO (109/L)	2.312 (1.324-4.035)	0.0031	2.488 (1.175-5.271)	0.0171
AST (U/L)	1.004 (0.998-1.010)	0.181	-	-
ALT (U/L)	1.004 (0.999-1.008)	0.150	-	-
GGT (U/L)	1.002 (0.999-1.005)	0.211	-	-
A/G ratio	0.198 (0.022-1.779)	0.148	-	-
ALBI grade	-	0.219	-	-
ALBI grade 1	0.877 (0.19-4.052)	0.867	-	-
ALBI grade 2	2.667 (0.572-12.428)	0.212	-	-

¹The significant risk factors or independent predictors of the preoperative pathological classification identified by a univariate or multivariate analysis.

CI: Confidence interval; OR: Odds ratio; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; LMR: Lymphocyte-to-monocyte ratio; HBV: Hepatitis B virus; AFP: Alpha-fetoprotein; PLT: Platelet; LYMPH: Lymphocyte; NEU: Neutrophil; MONO: Monocyte; AST: Aspartate aminotransferase; ALT: Alanine transaminase; GGT: Gamma-glutamyl transferase; A/G: Albumin/globulin; ALBI: Albumin-bilirubin index.