Susceptibility weighted imaging: Clinical applications and future directions

Figure 18 Example orthogonal views of quantitative susceptibility mapping images of a 41-year-old female premanifest HD patient showing the basal ganglia where increased tissue magnetic susceptibility can be observed in iron-rich gray matter structures such as the caudate nuclei and putamen. Extra iron overload in the striatum in these patients as compared to age-matched controls is believed to be associated with HD pathophysiology. Gray scale is in [-0.2, 0.2] ppm.