Contrast-enhanced harmonic ultrasound imaging in ablation therapy for primary hepatocellular carcinoma

Figure 2 Indications for contrast-enhanced ultrasound (US) in radiofrequency (RF) ablation therapy. A: Local tumor progression or residual hepatic malignancies. Contrast-enhanced US shows not only the tumor but also ablated areas as a defect image in the post vascular phase. However, viable tumor is enhanced by reinjection of Sonazoid; B: Hepatic malignancies with severe cirrhotic change. The true malignant tumor was sited among many large regenerated nodules in cirrhotic liver. On contrast-enhanced US, the tumor was distinguishable by reinjection of Sonazoid.