Observational Study
Copyright ©The Author(s) 2017.
World J Cardiol. May 26, 2017; 9(5): 448-456
Published online May 26, 2017. doi: 10.4330/wjc.v9.i5.448
Table 1 Clinical and biochemical characteristics from patients with celiac disease and control subjects
Patients with celiac disease (n = 20)Control subjects (n = 20)P
Age (yr)50 (25-58)47 (28-60)ns
Men/woman5/155/15ns
BMI (kg/m2)22.8 (20.4-26.2)23.0 (21.0-24.7)ns
Glucose (mg/dL)87 ± 1186 ± 12ns
Insulin (mU/L)7.2 (5.0-11.3)4.6 (2.6-6.7)< 0.05
HOMA-IR1.45 (1.04-2.24)1.00 (0.51-1.45)< 0.05
QUICKI0.33 (0.28-0.40)0.42 (0.34-0.65)< 0.05
Urea (mg/dL)27 (21-34)35 (34-39)< 0.01
Creatinine (mg/dL)0.74 (0.63-0.88)0.80 (0.75-1.10)< 0.05
Uric acid (mg/dL)5.0 ± 1.24.3 ± 1.6ns
Bilirubin (mg/dL)0.7 (0.5-0.8)0.6 (0.6-0.8)ns
ASAT (U/L)26 (20-35)14 (12-20)< 0.01
ALAT (U/L)22 (17-39)18 (16-22)ns
ALP (U/L)80 (59-102)124 (67-219)ns
Table 2 Hematological parameters from patients with celiac disease and control subjects
Patients with celiac disease (n = 20)Control subjects (n = 20)P
Erythrocytes (106/mL)4.40 ± 0.484.58 ± 0.27ns
Hematocrite (%)38.5 ± 4.040.1 ± 2.6ns
Hemoglobin (g/dL)13.0 ± 1.413.3 ± 0.9ns
Serum iron (µg/dL)73 ± 35105 ± 61ns
Ferritin (ng/mL)33 (13-110)92 (43-117)ns
Transferrin (mg/dL)261 ± 62293 ± 59ns
Transferrin Sat. (%)25 ± 1429 ± 14ns
Vitamin B12 (pg/mL)337 (251-482)315 (265-393)ns
Folic acid (ng/mL)5.4 (4.4-7.9)12.2 (8.0-14.2)< 0.01
Table 3 Lipid, lipoprotein and apolipoprotein profile from patients with celiac disease and control subjects
Patients with celiac disease (n = 20)Control subjects (n = 20)P
TG (mg/dL)81 (65-119)78 (60-114)ns
TC (mg/dL)185 ± 37194 ± 39ns
VLDL-C (mg/dL)18 ± 817 ± 7ns
LDL-C (mg/dL)139 (89-149)107 (95-147)ns
HDL-C (mg/dL)45 ±1557 ±17< 0.05
Non-HDL-C (mg/dL)153 (105-167)137 (112-167)ns
Apo A-I (mg/dL)130 ± 31155 ± 29< 0.05
Apo B (mg/dL)93.6 ± 23.883.5 ± 20.7ns
TG/HDL-C2.09 (1.13-2.98)1.29 (1.06-1.93)ns
TC/HDL-C4.19 (3.11-5.00)3.52 (2.84-4.08)< 0.05
ApoB/apo A-I0.75 ± 0.250.55 ± 0.16< 0.01