Influence of hospital volume and outcomes of adult structural heart procedures

Table 1 Multivariate regression for different outcomes during transcatheter aortic valve repair

	Multivariate simple logistic regression for mortality		Multivariate simple logistic regression for any complications and mortality		Multivariate simple logistic regression for LOS (LOS ≥ 6 d)		Multivariate simple logistic regression for disposition of transfer to short-term hospital/other facilities/home health care
Variable	OR (95%CI)	P value	OR (95%CI)	P value	OR (95%CI)	P value	OR (95%CI)	P value
Hospital volume quartile
1st quartile	1	Referent	1	Referent	1	Referent	1	Referent
2nd quartile	0.92 (0.70-1.21)	0.550	0.86 (0.76-0.99)	0.029	0.82 (0.71-0.94)	0.004	1.06 (0.91-1.23)	0.451
3rd quartile	0.80 (0.60-1.06)	0.114	0.70 (0.61-0.80)	< 0.001	0.91 (0.80-1.05)	0.194	0.65 (0.56-0.75)	< 0.001
4th quartile	0.38 (0.27-0.54)	< 0.001	0.71 (0.62-0.82)	< 0.001	0.85 (0.74-0.98)	0.024	0.77 (0.66-0.90)	0.001
Access
Transfemoral	1	Referent	1	Referent	1	Referent	1	Referent
Trans-apical	1.54 (1.17-2.03)	0.002	1.44 (1.26-1.64)	< 0.001	2.27 (1.96-2.63)	< 0.001	1.37 (1.18-1.60)	< 0.001
Age (10-yr increment)	1.26 (1.07-1.47)	0.005	0.97 (0.91-1.03)	0.316	1.07 (1.00-1.14)	0.051	1.57 (1.46-1.69)	< 0.001
Gender
Male	1	Referent	1	Referent	1	Referent	1	Referent
Female	1.09 (0.89-1.36)	0.392	1.21 (1.11-1.33)	< 0.001	1.43 (1.30-1.57)	< 0.001	1.99 (1.79-2.21)	< 0.001
Charlson score
0	1	Referent	1	Referent	1	Referent	1	Referent
1	1.29 (0.78-2.14)	0.321	1.13 (0.92-1.38)	0.236	1.23 (1.01-1.50)	0.038	1.40 (1.14-1.72)	0.002
≥ 2	1.60 (1.01-2.55)	0.047	1.73 (1.44-2.08)	< 0.001	2.02 (1.69-2.42)	< 0.001	1.72 (1.42-2.07)	< 0.001
Bed size of hospital
Small	1	Referent	1	Referent	1	Referent	1	Referent
Medium	0.43 (0.28-0.67)	< 0.001	0.89 (0.70-1.15)	0.386	1.18 (0.91-1.52)	0.215	1.17 (0.88-1.56)	0.279
Large	0.42 (0.29-0.61)	< 0.001	0.73 (0.58-0.91)	0.005	1.36 (1.09-1.71)	0.007	1.23 (0.96-1.58)	0.103
Model 2
Hospital volume quartile (5 procedures increment)	0.88 (0.83-0.93)	< 0.001	0.94 (0.92-0.95)	< 0.001	0.93 (0.91-0.95)	< 0.001	0.95 (0.94-0.97)	< 0.001
Model 3
Hospital volume quartile (10 procedures increment)	0.77 (0.69-0.86)	< 0.001	0.87 (0.84-0.91)	< 0.001	0.87 (0.84-0.90)	< 0.001	0.91 (0.87-0.95)	< 0.001

LOS: Length of stay; OR: Odds ratio.