Comparison between the SAPIEN S3 and the SAPIEN XT transcatheter heart valves: A single-center experience

doi:10.4330/wjc.v8.i12.735

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World Journal of Cardiology

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1949-8462

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Cardiol. Dec 26, 2016; 8(12): 735-745
Published online Dec 26, 2016. doi: 10.4330/wjc.v8.i12.735

Table 1 Baseline characteristics

Variable	S3-THV (n = 283)	XT-THV (n = 507)	P value
Age	82.8 ± 7.1	83.5 ± 7.0	0.14
Female sex	137 (48.4)	275 (54.3)	0.12
STS-PROM, %	5.3 ± 3.5	6.4 ± 4.0	< 0.0001
Logistic EuroSCORE, %	15.7 ± 10.8	18.8 ± 11.5	< 0.0001
NYHA class 3 or 4	162 (59.1)	383 (75.8)	< 0.0001
History of syncope	1 (0.5)	10 (2.1)	0.19
Atrial arrhythmia (flutter or fibrillation)	80 (29.5)	135 (27.8)	0.67
Diabetes	71 (25.1)	124 (24.5)	0.86
Hypertension	161 (71.6)	344 (68.8)	0.49
Dyslipidemia	99 (44.0)	263 (52.6)	0.04
Active smoker	4 (1.4)	18 (3.6)	0.11
Previous PPM	35 (12.4)	60 (11.8)	0.91
Previous PCI	81 (29.3)	114 (22.9)	0.06
Previous CABG	25 (9.0)	51 (10.3)	0.62
Previous SAVR	2 (0.7)	7 (1.4)	0.5
Previous stroke	25 (8.8)	39 (7.7)	0.59
Peripheral vascular disease	56 (19.8)	143 (28.4)	0.01
eGFR, mL/min per 1.73 m²	62.8 ± 24.6	61.4 ± 22.6	0.42
eGFR < 40 mL/min per 1.73 m²	82 (16.2)	41 (14.5)	0.61
Dialysis	4 (1.5)	13 (2.6)	0.44
Chronic obstructive pulmonary disease	33 (11.7)	110 (21.9)	< 0.0001
Body mass index, kg/m²	26.5 ± 5.1	26.3 ± 4.9	0.61
LVEF, %	54.9 ± 14.8	53.6 ± 14.2	0.24
LVEF < 30%	55 (11.1)	31 (11.4)	0.91
Mean aortic gradient, mmHg	46.7 ± 15.3	46.9 ± 15.3	0.92
AVA, cm²	0.67 ± 0.17	0.65 ± 0.14	0.31
Pulmonary artery systolic pressure, mmHg	44.5 ± 13.0	46.5 ± 12.9	0.06
Pulmonary artery systolic pressure > 50 mmHg	64 (28.3)	123 (28.5)	1

Values are mean ± SD or n (%). AVA: Aortic valve area; CABG: Coronary artery bypass graft; eGFR: Glomerular filtration rate estimated by the MDRD formula; EuroSCORE: European System for Cardiac Operative Risk Evaluation; LVEF: Left ventricular ejection fraction; NYHA: New York Heart Association functional class; PPM: Permanent pacemaker; PCI: Percutaneous coronary intervention; SAVR: Surgical aortic valve replacement; STS-PROM: Society of Thoracic Surgeons Predicted Risk of Mortality; S3-THV: SAPIEN 3 transcatheter heart valve; XT-THV: SAPIEN XT transcatheter heart valve.

Citation: Sawaya FJ, Spaziano M, Lefèvre T, Roy A, Garot P, Hovasse T, Neylon A, Benamer H, Romano M, Unterseeh T, Morice MC, Chevalier B. Comparison between the SAPIEN S3 and the SAPIEN XT transcatheter heart valves: A single-center experience. World J Cardiol 2016; 8(12): 735-745
URL: https://www.wjgnet.com/1949-8462/full/v8/i12/735.htm
DOI: https://dx.doi.org/10.4330/wjc.v8.i12.735