Genetics of coronary artery disease and myocardial infarction

Table 3 Genetic variants associated with a reduced risk of coronary artery disease/myocardial infarction (protective factors against coronary artery disease/myocardial infarction)

Chr	Gene	Protective alleles	Ref.
1p13	Rs599839 A>GRs646776 T>C	C/G haplotype	[161,162]
1q22	E-selectin	G2692A; C901T	[163]
1q31	GLUL	Rs10911021 T>C, TT allele	[164]
1q31	IL-10	G(-1082)A, GG genotype	[165]
1p34	LRP 8	TCCGC	[166]
2p21	ABCG 5/8	Rs41360247	[167]
3p25	PPARγ2	Pro12Ala homo	[168-170]
3p25	PPARγ	C161T	[171]
3q27	Adiponectin	Rs1501299 (G276T), TT allele	[172-174]
8q21	FABP4	Rs77878271	[175]
6p12.3	PLA2G7	R92H	[176]
6p25.3	FXIII	Val34Liu	[177,178]
7q21.3	PON1/2	Gln192Arg	[112,116]
7q32.3	KLF14	Rs4731702 T/T allele	[179]
7q36	INSIG1	Hap3 (T/G/A)	[180]
9q31.1	ABCG1	G1051A, r219K, KK allele	[78]
11q23.3	APOC3	R19X	[181]
13q34	FVII	R353Q; QQ allele A2 allele (without a 10 bp insertion)	[182]
16q13	FKN	T280M allele; Rs4329913; Rs7202364	[183,184]
16q24	NADPH p22phox	C242T	[185,186]
17p13.2	GP1bα	Thr/Th; TT haplotype	[187]
21q22.1	MRPS6	C699T (TT) or T1080C (CC)	[64]