Effective treatment of depression improves post-myocardial infarction survival

Table 2 Results of separate Cox regression analyses to examine the contributions of each biological, social and psychological predictor to mortality among treated post- myocardial infarction patients with depression (n = 770)

	B	SE	Wald	Sig.	HR	95%CI
Biological factors
Age1	0.048	0.011	19.205	< 0.001	1.05	1.027-1.073
Female gender	0.741	0.266	7.791	0.005	2.098	1.247-3.531
Minority status	0.020	0.272	0.005	0.943	1.020	0.599-1.737
Diabetes	1.448	0.272	28.401	< 0.001	4.255	2.498-7.247
Heart failure	1.495	0.275	29.507	< 0.001	4.461	2.601-7.652
Hypertension	1.002	0.322	9.675	0.002	2.723	1.449-5.120
Prior MI	0.961	0.261	13.533	< 0.001	2.616	1.567-4.365
Prior stroke	1.165	0.306	14.496	< 0.001	3.207	1.760-5.843
Current smoker	-1.128	0.361	9.781	0.002	0.324	0.160-0.656
Social factors
Live alone	0.552	0.258	4.591	0.032	1.737	1.048-2.880
Perceived social support	-0.046	0.028	2.768	0.096	0.955	0.904-1.008
Social isolation	-0.197	0.258	0.582	0.446	0.822	0.496-1.361
Psychological factor
Baseline depression symptom severity	< 0.001	0.016	0.001	0.978	1.000	0.968-1.032
Treatment resistant depression	0.534	0.312	2.927	0.087	1.705	0.925-3.143

¹Age centered on the lowest age of 34 years. For dichotomous variables reference group is the absence of the named predictor. MI: Myocardial infarction.