Renal function assessment in atrial fibrillation: Usefulness of chronic kidney disease epidemiology collaboration vs re-expressed 4 variable modification of diet in renal disease

Table 1 Baseline characteristics n (%)

Age (yr)	73 ± 11
Men	605 (66.4)
Systolic blood pressure at study entry	139 ± 28
Hypertension	678 (74.4)
Current smoking	77 (8.5)
Diabetes mellitus	220 (24.1)
Heart failure	343 (37.7)
Peripheral arterial disease	92 (10.1)
History of stroke or TIA	103 (11.3)
Coronary artery disease	127 (13.9)
COPD	183 (20.1)
CHA2DS2-VASc:
= 0	62 (6.8)
≥ 1	849 (93.2)
≥ 2	772 (84.7)
History of malignancy	135 (14.8)
HAS-BLED
0	47 (5.2)
1	160 (17.6)
2	365 (40.1)
3	261 (28.6)
4	69 (7.6)
5	6 (0.7)
6	3 (0.3)
Alcohol consumption ≥ 40 g/daily	81 (8.9)
Prior bleeding	115 (12.6)
Anemia	178 (19.5)
Abnormal liver function1	9 (1)
PINRR	58% ± 18%

¹Defined as cirrhosis or elevated liver transaminases enzymes > 3 times higher than the upper limit of normal and elevated total billirubin > 2 times higher than the upper limit of normal. CHA2DS2-VASc: Congestive heart failure, hypertension, age ≥ 75, diabetes mellitus, stroke, vascular disease, female sex category; COPD: Chronic obstructive pulmonary disease; HAS-BLED: Uncontrolled Hypertension: systolic > 160 mmHg, Abnormal renal/liver function, Stroke, Bleeding history or predisposition, Labile international normalized ratio, elderly > 65 years, drugs/alcohol concomitantly; TIA: Transient ischemic attack; PINRR: Percentage of INRs in therapeutic range.