Physiology of natriuretic peptides: The volume overload hypothesis revisited

doi:10.4330/wjc.v6.i1.4

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Jan 26, 2014 (publication date) through Jun 15, 2024

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World Journal of Cardiology

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1949-8462

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Cardiol. Jan 26, 2014; 6(1): 4-7
Published online Jan 26, 2014. doi: 10.4330/wjc.v6.i1.4

Table 2 Novel insights

New information 1	Natriuretic peptide system responds to oxygen tension (hypoxia-response elements in the promoter sequence of ANP and BNP genes). Volume overload causes wall stress and changes the consumption or diffusion of oxygen in heart
New information 2	The result of natriuresis, diuresis and plasma shift is volume contraction and increased oxygen-carrying capacity per unit volume of blood. Oxygen transport will be enhanced

ANP: Atrial natriuretic peptide; BNP: Brain natriuretic peptide.

Citation: Arjamaa O. Physiology of natriuretic peptides: The volume overload hypothesis revisited. World J Cardiol 2014; 6(1): 4-7
URL: https://www.wjgnet.com/1949-8462/full/v6/i1/4.htm
DOI: https://dx.doi.org/10.4330/wjc.v6.i1.4