Mechanisms of drug-induced proarrhythmia in clinical practice

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Jun 26, 2013 (publication date) through Apr 18, 2024

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World Journal of Cardiology

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1949-8462

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Cardiol. Jun 26, 2013; 5(6): 175-185
Published online Jun 26, 2013. doi: 10.4330/wjc.v5.i6.175

Table 2 Agents implicated in drug-induced Brugada electrocardiographic pattern

Category	Drugs
Antiarrhythmic	Ajmaline, flecainide, pilsicainide, procainamide, propafenone
Antidepressant	Amitriptyline, nortriptyline, clomipramine, desipramine, imipramine, doxepin, dosulepine, maprotiline, lithium, fluoxetine, paroxetine, fluvoxamine,
Antipsychotic	Loxapine, trifluoperazine, cyamemazine, perphenazine, thioridazine
Anti-epileptic	Oxcarbazepine
Anesthetics/analgesics	Bupivacaine, propofol
Antihistamines	Diphenhydramine, dimenhydrinate
Other substances	Cocaine, alcohol, metoclopramide, acetylcholine, ergonovine maleate, edrophonium

The full list can be accessed via the internet (http://www.brugadadrugs.org).

Citation: Konstantopoulou A, Tsikrikas S, Asvestas D, Korantzopoulos P, Letsas KP. Mechanisms of drug-induced proarrhythmia in clinical practice. World J Cardiol 2013; 5(6): 175-185
URL: https://www.wjgnet.com/1949-8462/full/v5/i6/175.htm
DOI: https://dx.doi.org/10.4330/wjc.v5.i6.175