Ultrasound-assessed non-culprit and culprit coronary vessels differ by age and gender

Table 1 Baseline characteristics (n = 130) n (%)

Characteristic	Patients in the lowest age tertile	Patients in the middle age tertile	Patients in the highest age tertile	P value1
Age, mean ± SD (range), yr	47.6 ± 6.8 (20.5-55.5)	59.6 ± 2.4 (55.5-64.2)	70.9 ± 4.8 (64.3-83.7)	< 0.001
Female sex	29 (22.3)	36 (27.7)	43 (33.1)	0.053
Body mass index, mean ± SD, kg/m2	26.9 ± 5.1	28.0 ± 4.9	27.4 ± 3.6	0.408
Obesity2	25 (19.2)	37 (28.5)	30 (23.1)	0.466
Systolic BP, mean ± SD, mmHg	128 ± 19	134 ± 19	133 ± 20	0.017
Diastolic BP, mean ± SD, mmHg	77 ± 12	77 ± 11	73 ± 11	0.007
Cardiovascular risk factors
Hypertension	58 (44.6)	85 (65.4)	95 (73.1)	< 0.001
Dyslipidemia	77 (59.2)	101 (77.7)	90 (69.2)	0.082
Current smoker	47 (36.2)	30 (23.1)	16 (12.3)	< 0.001
Diabetes	11 (8.5)	23 (17.7)	30 (23.1)	0.001
Positive family history	47 (36.2)	48 (36.9)	51 (39.2)	0.609
Manifest atherosclerosis
CAD	78 (60.0)	101 (77.7)	112 (86.2)	< 0.001
ACS	35 (26.9)	32 (24.6)	33 (25.4)	0.777
Previous stroke	1 (0.8)	5 (3.9)	7 (5.4)	0.038
Peripheral artery disease	2 (1.5)	11 (8.5)	6 (4.6)	0.250
Medication3
ACE inhibitor	29 (22.3)	46 (35.4)	52 (40.0)	0.002
Betablocker	47 (36.2)	60 (46.2)	67 (51.5)	0.013
Statin	36 (27.7)	57 (43.9)	62 (47.7)	0.001
Other measurements
LDL, mean ± SD, mmol/L	2.8 ± 1.0	2.7 ± 1.2	2.6 ± 1.0	0.263
LVEF, mean ± SD, %	70 ± 11	68 ± 13	70 ± 12	0.875

¹P value for trend across age groups was calculated using linear regression;

²Defined as body mass index ≥ 30 kg/m²;

³Long-term medication in the two weeks before intravascular ultrasound. ACE: Angiotensin converting enzyme; ACS: Acute coronary syndrome; BP: Blood pressure; CAD: Coronary artery disease; LDL: Low-density lipoprotein cholesterol.