Positive influence of aspirin on coronary endothelial function: Importance of the dose

Table 3 Hemodynamics and angiographic results between groups I and II (mean ± SE)

	Group I	Group II	P value
Baseline mean BP(mmHg)	107 ± 2	104 ± 1	NS
Baseline heart rate (/min)	66 ± 1	67 ± 1	NS
Coronary diameter
Baseline (mm)	3.22 ± 0.07	3.07 ± 0.06	NS
ACh at 3 μg/min (mm)	3.28 ± 0.07	3.07 ± 0.07	NS
(% change)	1.8 ± 0.9	0.1 ± 0.8	NS
ACh at 30 μg/min (mm)	3.26 ± 0.08	2.95 ± 0.07	0.0030
(% change)	1.2 ± 1.1	-3.9 ± 1.0	0.0008
Nitroglycerin (mm)	3.67 ± 0.07	3.51 ± 0.07	NS
(% change)	14.0 ± 1.1	15.1 ± 1.0	NS
Coronary blood flow
Baseline (mL/min)	88.1 ± 3.7	81.9 ± 3.3	NS
ACh at 3 μg/min (mL/min)	131.3 ± 7.8	123.3 ± 7.1	NS
(% change)	50.0 ± 6.3	52.1 ± 5.7	NS
ACh at 30 μg/min (mm)	219.9 ± 21.4	194.8 ± 19.5	NS
(% change)	172.8 ± 33.2	142.6 ± 30.3	NS
Coronary flow reserve	3.4 ± 0.2	3.4 ± 0.1	NS

BP: Blood pressure; ACh: Acetylcholine; NS: Not significant.