Advances in diastolic heart failure

Table 1 The benefits of drugs in patients with DHF in different studies

	Diuretic	D + irbes	D + Ram	Digoxin	Candes	Perindo	Nebivo	irbes
n	50	56	45	492	3022	850	2128	4128
mean age (yr)	70	75	74	67	67	65	76	72
Female (%)	58	66	60	42	40	54	36	60
Mean LVEF (%)	69	66	65	50-71	54	65	36	59
Results
(52 wk) LV mass (g)	-11	-8	-7
QoL score	20.0-10.9	19.0-9.4	23.0-11.4
6 MWT (meter)	1011-1048	950-1007	962-1028
Benefits				No		No	No
Death					No			No
CV or CHF hospital					Yes			No
Ref.	[36]	[36]	[36]	[35]	[7]	[8]	[34]	[42]

D: Diuretic; irbes: Irbesartan; Ram: Ramipril; Candes: Candesartan; Perindo: Perindopril; Nebivo: Nebivolol; QoL: Quality of life; 6 MWT: 6 min walk test.