Cardiorespiratory coordination: Historical development of analysis methods, current state, and future research prospects

doi:10.4330/wjc.125211

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World Journal of Cardiology

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1949-8462

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World J Cardiol. Sep 26, 2026; 18(9): 125211
Published online Sep 26, 2026. doi: 10.4330/wjc.125211

Table 2 Pathophysiological substantiation of hypotheses about cardiorespiratory coordination changes in arterial hypertension

Pathway	Expected direction of cardiorespiratory coordination change	Substantiation
Reduced baroreflex sensitivity	Decrease (fewer coordinated heart beats)	Weakening of the afferent signal modulating respiration
Hypersympathicotonia	Increase (similar to sleep apnea and preeclampsia)	Increased central respiratory activity
Endothelial dysfunction	Indeterminate	Lack of direct data

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Citation: Dubinkina ES, Kiselev AR. Cardiorespiratory coordination: Historical development of analysis methods, current state, and future research prospects. World J Cardiol 2026; 18(9): 125211
URL: https://www.wjgnet.com/1949-8462/full/v18/i9/125211.htm
DOI: https://dx.doi.org/10.4330/wjc.125211

Dubinkina ES, Kiselev AR. Cardiorespiratory coordination: Historical development of analysis methods, current state, and future research prospects. World J Cardiol 2026; 18(9): 125211 [DOI: 10.4330/wjc.125211]

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