Triglyceride-glucose index and all-cause mortality in patients with chronic severe heart failure

Table 4 Multivariable Cox regression models for the association between triglyceride-glucose index and 5-year all-cause mortality

Model	Adjustment	n	Events	HR	95%CI	P value
Model 1	Unadjusted	261	135	1.46	1.14-1.87	0.003
Model 2	Age, sex, BMI	261	135	1.41	1.09-1.83	0.009
Model 3	Model 2 + diabetes mellitus, hypertension, eGFR, LVEF	261	135	1.36	1.04-1.78	0.025
Model 4	Model 3 + NT-proBNP, ACEI/ARB use, beta-blocker use	261	135	1.33	1.01-1.76	0.041

Hazard ratio refer to each 1-unit increase in triglyceride-glucose index. In models including N-terminal pro-brain natriuretic peptide (NT-proBNP), NT-proBNP was entered as a standardized continuous variable. HR: Hazard ratio; CI: Confidence interval; BMI: Body mass index; eGFR: Estimated glomerular filtration rate; LVEF: Left ventricular ejection fraction; NT-proBNP: N-terminal pro-brain natriuretic peptide; ACEI: Angiotensin-converting enzyme inhibitor; ARB: Angiotensin receptor blocker.