Circulating microRNAs as biomarkers of cardiovascular disease: A systematic review

Table 2 A Newcastle Ottawa scale summarizing the methodological quality of the included studies

Ref.	Selection	Comparability	Reporting	AHRQ standard
Klenke et al[15], 2018	3	2	3	Good
Shah et al[16], 2018	3	2	3	Good
Pilbrow et al[17], 2014	3	2	3	Good
Shen et al[18], 2021	3	2	3	Good
Biener et al[19], 2022	3	2	3	Good
Eyyupkoca et al[20], 2022	2	1	2	Fair
Cai et al[21], 2024	3	2	3	Good
Grabmaier et al[22], 2017	3	2	3	Good
Wang et al[23], 2011	3	2	3	Good
Devaux et al[24], 2015	3	2	3	Good
Jakob et al[25], 2017	3	2	3	Good
Matsumoto et al[26], 2013	3	2	3	Good
Cortez-Dias et al[27], 2016	2	2	3	Fair
He et al[28], 2014	3	2	3	Good
Bauters et al[29], 2013	3	2	3	Good
Hromádka et al[30], 2019	3	2	3	Good
Zeller et al[31], 2014	3	2	3	Good
Simionescu et al[32], 2016	3	2	3	Good
Wang et al[33], 2017	3	2	3	Good
Zhong et al[34], 2018	3	2	3	Good
Polyakova et al[35], 2021	3	2	3	Good
Karakas et al[36], 2017	3	2	3	Good
de Gonzalo-Calvo et al[37], 2019	3	2	3	Good
Wang et al[38], 2014	3	2	3	Good
Wang et al[39], 2020	3	2	3	Good
Yuan et al[40], 2018	3	2	3	Good
Opstad et al[41], 2017	3	2	3	Good
Iusupova et al[42], 2024	3	2	3	Good
Mayer et al[43], 2019	3	2	3	Good
Mick et al[44], 2017	3	2	3	Good
Mäntylä et al[45], 2025	3	2	3	Good
Yildirim et al[46], 2019	3	2	3	Good
Kara et al[47], 2021	3	2	3	Good
Jäntti et al[10], 2019	3	2	3	Good

AHRQ: Agency for Healthcare Research and Quality.