Landiolol attenuates atrial remodeling in septic rats by upregulating calumenin

Figure 5 Landiolol reduced endoplasmic reticulum stress-induced apoptosis in sepsis rat hearts. A: Transferase dUTP nick end labeling analysis of apoptosis in sepsis rat hearts; B: Immunohistochemistry analysis of glucose-regulated protein 78 (GRP78) and C/EBP homologous protein (CHOP) levels in rat hearts; C and D: Western blot analysis of GRP78 and CHOP levels in rat hearts; E: Quantitative analysis in immunohistochemistry analysis of CHOP; F: Quantitative analysis of CHOP; G: Quantitative analysis in immunohistochemistry analysis of GRP78; H: Quantitative analysis of GRP78. Results are shown as mean ± SD. ^cP < 0.001 vs control, ^eP < 0.01 vs sepsis; ^fP < 0.001 vs sepsis. Con: Control; CHOP: C/EBP homologous protein; GRP78: Glucose-regulated protein 78.