Prognostic value of glomerular-filtration-rate estimated by common and modified Asian/Chinese equations for cardiovascular outcomes in elderly Chinese individuals

Table 2 Association between clinical outcomes and estimated glomerular filtration rate calculated with different equations, n (%)

Equation	Event	eGFR(mL/minute)			P value
		≥ 90	60-90	< 60
MDRD	MACE	113 (9.5)	190 (10.5)	40 (15.9)1	0.011
	Cardiovascular mortality	16 (1.3)	42 (2.3)	19 (7.6)1	< 0.001
	All-cause mortality	54 (4.5)	95 (5.2)	53 (21.1)1	< 0.001
	Event-free	1037 (87.3)	1575 (86.6)	177 (70.5)1	< 0.001
c-aMDRD	MACE	170 (9.5)	137 (10.7)	36 (19.4)1	< 0.001
	Cardiovascular mortality	32 (1.8)	27 (2.1)	18 (9.7)1	< 0.001
	All-cause mortality	82 (4.6)	75 (5.9)	45 (24.2)1	< 0.001
	Event-free	1571 (87.7)	1095 (85.5)	123 (66.1)1	< 0.001
CKD-EPI	MACE	71 (8.6)	224 (10.7)	48 (14.4)1	0.015
	Cardiovascular mortality	7 (0.9)2	46 (2.2)	24 (7.2)1	< 0.001
	All-cause mortality	26 (3.2)2	111 (5.3)	65 (19.5)1	< 0.001
	Event-free	731 (89)2	1814 (86.3)	244 (73.3)1	< 0.001
aCKD-EPI	MACE	122 (8.8)2	180 (11.1)	41 (16.3)1	0.001
	Cardiovascular mortality	12 (0.9)2	45 (2.8)	20 (7.9)1	< 0.001
	All-cause mortality	45 (3.3)2	102 (6.3)	55 (21.8)1	< 0.001
	Event-free	1224 (88.8)2	1389 (85.4)	176 (69.8)1	< 0.001
cCKD-EPI	MACE	12 (8.3)	254 (9.9)	77 (14.3)1	0.006
	Cardiovascular mortality	1 (0.7)	41 (1.6)	35 (6.5)1	< 0.001
	All-cause mortality	6 (4.1)	109 (4.2)	87 (16.2)1	< 0.001
	Event-free	128 (88.3)	2252 (87.5)	409 (76.0)1	< 0.001

¹Significant difference between estimated glomerular filtration rate < 60 and 60-90 (mL/minute).

²Significant difference between estimated glomerular filtration rate ≥ 90 and 60-90 (mL/minute).

MDRD: Modification of Diet in Renal Disease; c-aMDRD: Chinese-abbreviated Modification of Diet in Renal Disease; CKD-EPI: Chronic Kidney Disease Epidemiology Collaboration; aCKD-EPI: Asian-adapted Chronic Kidney Disease Epidemiology Collaboration; cCKD-EPI: Chinese-adapted Chronic Kidney Disease Epidemiology Collaboration; MACE: Major adverse cardiovascular events; eGFR: Estimated glomerular filtration rate.