Prognostic value of glomerular-filtration-rate estimated by common and modified Asian/Chinese equations for cardiovascular outcomes in elderly Chinese individuals

doi:10.4330/wjc.119376

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World Journal of Cardiology

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1949-8462

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Observational Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Cardiol. Jun 26, 2026; 18(6): 119376
Published online Jun 26, 2026. doi: 10.4330/wjc.119376

Table 1 Baseline characteristics based on estimated glomerular filtration rate values estimated with different equations, n (%)/median (interquartile range)

Variable	Total (n = 3257)	MDRD, < 90 mL/minute (n = 2069, 63.5%)	c-aMDRD, < 90 mL/minute (n = 1466, 45.0%)	CKD-EPI, < 90 mL/minute (n = 2436, 74.8%)	aCKD-EPI, < 90 mL/minute (n = 1878, 57.7%)	cCKD-EPI, < 90 mL/minute (n = 3112, 95.5%)
Age	70 (67-75)	71^a (68-77)	72^a (68-78)	71^a (68-77)	72^a (68-78)	70^a (67-75)
Male	1430 (43.9)	906 (43.8)	788^a (53.1)	1125^a (46.2)	855^a (45.5)	1428^a (45.9)
Hypertension	1740 (53.4)	1147^a (55.4)	848^a (57.8)	1349^a (55.4)	1074^a (57.2)	1674 (53.8)
Diabetes	639 (19.6)	374^a (18.1)	283 (19.3)	454^a (18.6)	351 (18.7)	599^a (19.2)
CHD	1050 (32.2)	703^a (34)	511^a (34.9)	838^a (34.4)	665^a (35.4)	1008 (32.4)
Stroke	612 (18.8)	394 (19)	285 (19.4)	458 (18.8)	355 (18.9)	588 (18.9)
Smoking	807 (24.8)	518 (25)	430^a (29.3)	606 (24.9)	475 (25.3)	805^a (25.9)
Alcoholic	556 (17.1)	334 (16.1)	236 (16.1)	409 (16.8)	303 (16.1)	537 (17.3)
BMI	24.4 (22.2-26.6)	24.4^a (22.4-26.8)	24.6^a (22.5-26.9)	24.4^a (22.3-26.7)	24.5^a (22.5-26.9)	24.4 (22.2-26.6)
TC	5.04 (4.41-5.73)	5.06^a (4.45-5.75)	5.02 (4.40-5.71)	5.04 (4.42-5.74)	5.04 (4.44-5.74)	5.03 (4.40-5.73)
LDL	3.09 (2.53-3.70)	3.11^a (2.57-3.72)	3.08 (2.55-3.68)	3.09 (2.55-3.71)	3.10 (2.56-3.71)	3.08 (2.53-3.69)
HDL	1.35 (1.13-1.61)	1.34 (1.13-1.61)	1.34 (1.11-1.62)	1.34 (1.13-1.62)	1.34 (1.12-1.63)	1.34 (1.13-1.61)
TG	1.38 (1.04-1.90)	1.35 (1.03-1.87)	1.36 (1.03-1.88)	1.36 (1.03-1.88)	1.36 (1.03-1.88)	1.38 (1.04-1.90)
WBC	5.66 (4.83-6.66)	5.74^a (4.92-6.72)	5.78^a (4.99-6.84)	5.7^a (4.87-6.71)	5.75^a (4.93-6.74)	5.66 (4.83-6.66)
Albumin	47 (45-49)	47^a (45-49)	47^a (45-48)	47^a (45-49)	47^a (45-48)	47 (45-49)
Uric acid	325 (275-380)	340^a (290-400)	355^a (301-416)	335^a (286-393)	343^a (292-403)	327^a (279-382)

^aP < 0.05 vs the subgroup with an estimated glomerular filtration rate ≥ 90 mL/minute/1.73 m².

CHD: Coronary heart disease; BMI: Body mass index; TC: Total cholesterol; LDL: Low-density lipoprotein; HDL: High-density lipoprotein; TG: Triglyceride; WBC: White blood cell count; MDRD: Modification of Diet in Renal Disease; c-aMDRD: Chinese-abbreviated Modification of Diet in Renal Disease; CKD-EPI: Chronic Kidney Disease Epidemiology Collaboration; aCKD-EPI: Asian-adapted Chronic Kidney Disease Epidemiology Collaboration; cCKD-EPI: Chinese-adapted Chronic Kidney Disease Epidemiology Collaboration.

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Citation: Aili A, Li RY, Mohammed AA, Zhao S, Li MR, Li HN, Xu YW, Zhang Y. Prognostic value of glomerular-filtration-rate estimated by common and modified Asian/Chinese equations for cardiovascular outcomes in elderly Chinese individuals. World J Cardiol 2026; 18(6): 119376
URL: https://www.wjgnet.com/1949-8462/full/v18/i6/119376.htm
DOI: https://dx.doi.org/10.4330/wjc.119376

Aili A, Li RY, Mohammed AA, Zhao S, Li MR, Li HN, Xu YW, Zhang Y. Prognostic value of glomerular-filtration-rate estimated by common and modified Asian/Chinese equations for cardiovascular outcomes in elderly Chinese individuals. World J Cardiol 2026; 18(6): 119376 [DOI: 10.4330/wjc.119376]

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