S1PR1 knockdown protects endothelial cells from oxidized low-density lipoprotein-induced injury via reducing interleukin-1β and tumor necrosis factor-α expression

doi:10.4330/wjc.v18.i5.120519

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World Journal of Cardiology

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1949-8462

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Cardiol. May 26, 2026; 18(5): 120519
Published online May 26, 2026. doi: 10.4330/wjc.v18.i5.120519

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Figure 1 Sphingosine-1-phosphate receptor 1 expression in different groups. A: Sphingosine-1-phosphate receptor 1 expression in control group (71 cases) and coronary atherosclerotic heart disease group (40 cases); B: Sphingosine-1-phosphate receptor 1 expression in low Gensini score group (48 cases) and high Gensini score group (23 cases). ^aP < 0.001 vs control, ^bP < 0.01 vs low score. S1PR1: Sphingosine-1-phosphate receptor 1; CAHD: Coronary atherosclerotic heart disease.

Citation: Chu FY, Yao MH, Gu LM, Cai H, Li YN, Chen X, Xu XX. S1PR1 knockdown protects endothelial cells from oxidized low-density lipoprotein-induced injury via reducing interleukin-1β and tumor necrosis factor-α expression. World J Cardiol 2026; 18(5): 120519
URL: https://www.wjgnet.com/1949-8462/full/v18/i5/120519.htm
DOI: https://dx.doi.org/10.4330/wjc.v18.i5.120519

Chu FY, Yao MH, Gu LM, Cai H, Li YN, Chen X, Xu XX. S1PR1 knockdown protects endothelial cells from oxidized low-density lipoprotein-induced injury via reducing interleukin-1β and tumor necrosis factor-α expression. World J Cardiol 2026; 18(5): 120519 [DOI: 10.4330/wjc.v18.i5.120519]

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