S1PR1 knockdown protects endothelial cells from oxidized low-density lipoprotein-induced injury via reducing interleukin-1β and tumor necrosis factor-α expression

Table 2 General clinical data analysis of low score group and high score group, n (%)/mean ± SD/median (interquartile range)

Clinical data	Low score (n = 48)	High score (n = 23)	χ2/t/U value	P value
Gender (male/female)	33/15	16/7	0.005	0.945
Age (years)	66.46 ± 1.64	69.03 ± 2.08	0.947	0.347
Systolic pressure (mmHg)	134 (123, 150)	135 (124, 145)	540.5	0.893
Diastolic pressure (mmHg)	83.5 (75, 88)	77 (71, 86)	425.0	0.120
Smoking history	20 (41.6)	15 (65.22)	3.450	0.063
Drinking history	23 (47.92)	13 (56.52)	0.461	0.497
FBG (mmol/L)	5.51 ± 0.35	6.24 ± 0.68	1.050	0.298
Cholesterol (mmol/L)	4.72 ± 0.14	5.30 ± 0.24	2.29	0.028
Triglyceride (mmol/L)	1.53 ± 0.10	1.69 ± 0.17	0.89	0.380
High-density lipoprotein-cholesterol (mmol/L)	1.26 (1.04, 1.45)	1.16 (0.98, 1.31)	446.0	0.195
Low-density lipoprotein-cholesterol (mmol/L)	2.88 ± 0.11	2.97 ± 0.14	0.49	0.630
Apolipoprotein A1 (g/L)	1.22 ± 0.05	1.16 ± 0.04	0.88	0.383
Apolipoprotein B (g/L)	0.84 ± 0.04	0.81 ± 0.06	0.37	0.712
Lipoprotein(a) (mg/L)	183 (100, 329)	309 (147, 608)	391	0.049
Alanine transaminase (U/L)	23.5 (16.25, 32)	20 (13, 35)	492	0.460
G-glutamyl transferase (U/L)	26 (18, 38.5)	26 (17, 41)	542.5	0.912
Uric acid (μmol/L)	342.0 ± 11.98	352.2 ± 19.02	0.470	0.640

FBG: Fasting blood glucose.