Metformin fails to prevent diabetes in non-diabetic cardiovascular patients: Systematic review and meta-analysis

doi:10.4330/wjc.v18.i4.115712

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World Journal of Cardiology

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1949-8462

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Cardiol. Apr 26, 2026; 18(4): 115712
Published online Apr 26, 2026. doi: 10.4330/wjc.v18.i4.115712

Table 5 Quality of reporting for eligible studies

Ref.	Random sequence generation (selection bias)	Allocation concealment (selection bias)	Blinding of participants and personnel (performance bias)	Blinding of outcome assessment (detection bias)	Incomplete outcome data (attrition bias)	Selective reporting (reporting bias)	Other bias
Preiss et al[22], 2014	L	L	L	L	L	L	L
Lexis et al[23], 2015	L	L	L	L	L	L	L
Hartman et al[24], 2017	L	L	L	L	L	L	L
Mohan et al[25], 2019	L	L	L	L	L	L	L

L: Low risk.

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Citation: Tsironikos GΙ, Zakynthinos GΕ, Kyprianidou D, Rammou V, Antonogiannis T, Bargiota A, Zakynthinos E, Tsolaki V. Metformin fails to prevent diabetes in non-diabetic cardiovascular patients: Systematic review and meta-analysis. World J Cardiol 2026; 18(4): 115712
URL: https://www.wjgnet.com/1949-8462/full/v18/i4/115712.htm
DOI: https://dx.doi.org/10.4330/wjc.v18.i4.115712

Tsironikos GΙ, Zakynthinos GΕ, Kyprianidou D, Rammou V, Antonogiannis T, Bargiota A, Zakynthinos E, Tsolaki V. Metformin fails to prevent diabetes in non-diabetic cardiovascular patients: Systematic review and meta-analysis. World J Cardiol 2026; 18(4): 115712 [DOI: 10.4330/wjc.v18.i4.115712]

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