Landiolol modulates sodium 1.5 ion and connexin-43 to reduce sepsis ventricular arrhythmias

Figure 4 Landiolol inhibits the production of inflammatory cells in the ventricular myocardium of sepsis rats and reduces myocardial cell apoptosis, thereby inhibiting fibrosis. A: Comparison of hematoxylin and eosin staining results in rat hearts; B: Quantitative comparison of Masson-stained myocardial fibrosis degree in the different experimental groups; C: Subcellular alterations in myocardial cells observed by confocal microscopy. From left to right in each column: Full-field view → FITC channel (green, target protein) → 4’-6-diamidino-2-phenylindole channel (blue, nuclei). Original magnification: 20 ×, n = 3.