Prognostic significance of vascular endothelial dysfunction in patients with vasospastic angina

doi:10.4330/wjc.v18.i3.116661

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World Journal of Cardiology

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1949-8462

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Cardiol. Mar 26, 2026; 18(3): 116661
Published online Mar 26, 2026. doi: 10.4330/wjc.v18.i3.116661

Table 3 Medications and vasospastic angina-related parameters at admission, n (%)/median (IQR)

	FMD-H group	FMD-L group	P value
Medications
Calcium-channel blockers	42 (34)	46 (38)	0.529
Long-acting nitrate	8 (7)	15 (12)	0.115
Nicorandil	9 (7)	8 (7)	0.829
RAS inhibitor	25 (20)	38 (31)	0.103
Beta-receptor blocker	7 (6)	14 (12)	0.102
Statins	52 (43)	37 (31)	0.058
Antiplatelet drug	24 (20)	24 (20)	0.950
Anti-DM drugs	11 (9)	11 (9)	0.968
Number of coronary vasodilators
At admission	0 (0, 1)	0 (0, 1)	0.444
At discharge	1 (1, 1)	1 (1, 1)	0.953
VSA-related parameters
Chest symptoms at rest, on exertion, and both	109/10/4	97/14/10	0.269
VA	1 (1)	2 (2)	0.552
Number of anginal attacks per month	4 (2, 10)	5 (2, 12)	0.524

FMD-H: High-flow-mediated dilation; FMD-L: Low-flow-mediated dilation; RAS: Renin-angiotensin system; DM: Diabetes mellitus; VSA: Vasospastic angina; VA: Variant angina.

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Citation: Teragawa H, Hashimoto Y, Tsuchiya A, Nomura S. Prognostic significance of vascular endothelial dysfunction in patients with vasospastic angina. World J Cardiol 2026; 18(3): 116661
URL: https://www.wjgnet.com/1949-8462/full/v18/i3/116661.htm
DOI: https://dx.doi.org/10.4330/wjc.v18.i3.116661

Teragawa H, Hashimoto Y, Tsuchiya A, Nomura S. Prognostic significance of vascular endothelial dysfunction in patients with vasospastic angina. World J Cardiol 2026; 18(3): 116661 [DOI: 10.4330/wjc.v18.i3.116661]

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