Prognostic significance of vascular endothelial dysfunction in patients with vasospastic angina

Table 2 Blood biochemical and echocardiographic parameters, mean ± SD

	FMD-H group	FMD-L group	P value
Blood biochemical parameters
Total cholesterol (mg/dL)	199 ± 29	197 ± 36	0.630
Triglyceride (mg/dL)	136 ± 76	139 ± 69	0.710
HDL-cholesterol (mg/dL)	60 ± 17	58 ± 17	0.359
LDL-cholesterol (mg/dL)	112 ± 26	111 ± 32	0.731
FBS (mg/dL)	105 ± 27	104 ± 18	0.831
HbA1c (%)	5.9 ± 0.7	5.9 ± 0.6	0.959
CRP (mg/dL), median (IQR)	0.06 (0.02, 0.18)	0.07 (0.03, 0.17)	0.268
BNP (pg/mL), median (IQR)	18 (9, 35)	23 (15, 50)	0.005
	n = 120	n = 119
eGFR (mL/minute/1.73 m2)	71.4 ± 15.9	68.7 ± 15.3	0.184
Echocardiographic parameters
LVEF (%)	67 ± 8	68 ± 9	0.513
Brachial ultrasound
Baseline brachial artery diameter (mm)	3.8 ± 0.6	4.0 ± 0.6	0.027
FMD (%)	5.9 ± 4.2	1.7 ± 1.6	< 0.001
NID (%)	16.4 ± 6.8	13.2 ± 6.3	0.002
	n = 120	n = 118

FMD-H: High-flow-mediated dilation; FMD-L: Low-flow-mediated dilation; HDL: High-density lipoprotein; LDL: Low-density lipoprotein; FBS: Fasting blood sugar; HbA1c: Hemoglobin A1c; CRP: C-reactive protein; IQR: Interquartile range; BNP: Brain natriuretic peptide; eGFR: Estimated glomerular filtration rate; LVEF: Left ventricular ejection fraction; FMD: Flow-mediated dilation; NID: Nitroglycerin-induced dilation.