Coronary computed tomography angiography adipose tissue attenuation in diabetic patients with myocardial ischemia and non-obstructive coronary arteries

doi:10.4330/wjc.v18.i1.112857

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World Journal of Cardiology

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1949-8462

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Cardiol. Jan 26, 2026; 18(1): 112857
Published online Jan 26, 2026. doi: 10.4330/wjc.v18.i1.112857

Table 1 Comparison of the patients’ baseline characteristics among groups, median (interquartile range)/n (%)/mean ± SD

	Healthy control group (n = 120)	Non-INOCA group (n = 118)	INOCA group (n = 110)
Clinical characteristics
Age (years)	56 (50-62)	66 (58-74)^a	69 (60.75-76)^a^,^b
Gender (female)	66 (55.0)	61 (51.7)	72 (62.5)^a^,^b
BMI, kg/m²	22.82 (20.81-24.21)	24.98 (23.42-27.07)^a	24.22 (21.74-26.31)^a^,^b
Smoking	29 (24.16)	34 (28.8)	46 (41.8)^a^,^b
Drinking	32 (26.67)	36 (30.5)	35 (31.8)
SBP, mmHg	122 (112-130)	133 (124-141.25)^a	137 (123.75-148.5)^a
DBP, mmHg	77.63 ± 12.21	82.36 ± 10.85^a	80.40 ± 13.98
Laboratory tests
TG, mmol/L	1.19 (0.92-1.60)	1.49 (1.01-2.31)^a	1.35 (1.05-1.94)^a
LDL-C, mmol/L	2.60 (2.19-3.08)	2.55 (1.90-3.14)	2.12 (1.50-2.65)^a^,^b
TC, mmol/L	4.64 ± 1.06	4.71 ± 1.22	4.10 ± 1.22^a^,^b
HDL-C, mmol/L	1.27 (1.04-1.48)	1.12 (0.96-1.35)^a	1.08 (0.89-1.25)^a^,^b
Fast glucose, mmol/L	5.09 (4.47-5.49)	7.26 (6.07-8.42)^a	7.91 (6.75-10.43)^a^,^b
HbA1c (%)	5.87 (5.64-6.12)	7.14 (6.68-7.85)^a	7.76 (7.02-9.46)^a^,^b
WBC, × 10 ⁹/L	5.55 (4.81-7.14)	6.43 (5.26-8.10)	6.62 (5.28-8.01)
NEU, × 10 ⁹/L	3.44 (2.67-4.38)	4.06 (3.16-5.27)	4.17 (3.17-5.60)
LYM, × 10 ⁹/L	1.67 (1.34-2.03)	1.75 (1.35-2.14)	1.54 (1.18-1.84)^b
MONO, × 10 ⁹/L	0.32 (0.26-0.42)	0.38 (0.29-0.49)	0.38 (0.31-0.51)
PLT, × 10 ⁹/L	196.18 ± 63.42	192.8 ± 57.88	175.95 ± 58.87^b
Medication situation
Antiplatelet agents		44 (37.3)	74 (67.3)^b
Diuretics		10 (8.5)	15 (13.6)
β-blockers		23 (19.5)	25 (22.7)
ACEI/ARB		31 (26.3)	30 (27.3)
Statins		65 (55.1)	86 (78.2)^b
CCBs		39 (33.1)	46 (41.8)
Hypoglycemic agents		72 (61.0)	78 (70.9)
Insulin therapy		19 (16.1)	43 (39.1)^b

^aP < 0.05 vs control group.

^bP < 0.05 vs non-ischemia with non-obstructive coronary artery disease group.

BMI: Body mass index; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; TG: Triglycerides; LDL-C: Low-density lipoprotein cholesterol; TC: Total cholesterol; HDL-C: High-density lipoprotein cholesterol; HbA1c: Glycated hemoglobin; WBC: White blood cell; NEU: Neutrophil; LYM: Lymphocyte; MONO: Monocyte; PLT: Platelet; ACEI: Angiotensin-converting enzyme inhibitor; ARB: Angiotensin receptor blocker; CCB: Calcium channel blocker; INOCA: Ischemia with non-obstructive coronary arteries.

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Citation: Su KX, Jiang SY, Pang CF, Yang F, Tang YQ, Li XG, He WF, Li R. Coronary computed tomography angiography adipose tissue attenuation in diabetic patients with myocardial ischemia and non-obstructive coronary arteries. World J Cardiol 2026; 18(1): 112857
URL: https://www.wjgnet.com/1949-8462/full/v18/i1/112857.htm
DOI: https://dx.doi.org/10.4330/wjc.v18.i1.112857

Su KX, Jiang SY, Pang CF, Yang F, Tang YQ, Li XG, He WF, Li R. Coronary computed tomography angiography adipose tissue attenuation in diabetic patients with myocardial ischemia and non-obstructive coronary arteries. World J Cardiol 2026; 18(1): 112857 [PMID: 41607616 DOI: 10.4330/wjc.v18.i1.112857]

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