Impact of total occlusion of the infarct-related coronary artery on mortality of 2483 patients with acute myocardial infarction

doi:10.4330/wjc.v18.i1.111736

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World Journal of Cardiology

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1949-8462

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Cardiol. Jan 26, 2026; 18(1): 111736
Published online Jan 26, 2026. doi: 10.4330/wjc.v18.i1.111736

Table 1 Demographic characteristics, comorbidities, atherosclerotic disease, and chronic therapy, n (%)

Variable	Occluded artery (n = 1687, 67.9%)	Patent artery (n = 796, 32.1%)	P value
Age (years)	63 (55-73)	66.3 (58-75)	< 0.0001
Male sex	1206 (72.9)	572 (71.87)	0.584
Comorbidities
Atrial fibrillation	95 (5.7)	65 (8.2)	0.018
Arterial hypertension	1176 (71.1)	624 (78.4)	< 0.0001
Diabetes mellitus	346 (20.9)	236 (29.6)	< 0.0001
Family history of CV diseases	545 (33.0)	280 (35.2)	0.649
Smoking	676 (40.6)	278 (34.9)	< 0.001
BMI (kg/m²)	27.8 (25.3-30.9)	27.8 (25.0-30.5)	0.388
Extent of atherosclerotic disease
Carotid stenosis	60 (3.6)	54 (6.8)	< 0.0001
Peripheral artery disease	89 (5.4)	66 (8.3)	< 0.005
Previous CABG	26 (1.6)	14 (1.8)	0.735
Previous PCI	140 (8.5)	89 (11.2)	0.030
Previous MI	166 (10.0)	117 (14.7)	< 0.0001
Previous stroke	83 (5.0)	46 (5.8)	0.427
Chronic therapy (> 4 weeks before AMI)
ASA	269 (16.3)	178 (22.4)	< 0.0001
ACEi/ARB	618 (37.4)	335 (22.1)	0.005
Beta-blockers	372 (22.5)	225 (28.3)	< 0.0001
Statins	255 (15.4)	174 (21.9)	< 0.0001

CV: Cardiovascular; BMI: Body mass index; CABG: Coronary artery bypass grafting; PCI: Percutaneous coronary intervention; AMI: Acute myocardial infarction; ASA: Acetylsalicylic acid; ACEi/ARB: Angiotensin-converting enzyme inhibitor/angiotensin receptor blocker.

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Citation: Kos N, Zeljković I, Golubic K, Radeljic V, Erceg M, Delic-Brkljacic D, Cigrovski Berkovic M, Bulj N. Impact of total occlusion of the infarct-related coronary artery on mortality of 2483 patients with acute myocardial infarction. World J Cardiol 2026; 18(1): 111736
URL: https://www.wjgnet.com/1949-8462/full/v18/i1/111736.htm
DOI: https://dx.doi.org/10.4330/wjc.v18.i1.111736

Kos N, Zeljković I, Golubic K, Radeljic V, Erceg M, Delic-Brkljacic D, Cigrovski Berkovic M, Bulj N. Impact of total occlusion of the infarct-related coronary artery on mortality of 2483 patients with acute myocardial infarction. World J Cardiol 2026; 18(1): 111736 [PMID: 41607612 DOI: 10.4330/wjc.v18.i1.111736]

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