Correlation of APOE, SLCO1B1 and LPA KIV-2 gene polymorphisms with coronary heart disease in the Teochew population

Table 4 Comparison of blood lipid levels among APOE genes

	E2 (n = 42)	E3 (n = 226)	E4 (n = 52)	P value
TG, mmol/L	1.62 ± 0.89	1.59 ± 1.10	2.09 ± 0.73a	0.022
TC, mmol/L	4.57 ± 1.22	4.72 ± 1.26	5.47 ± 1.70a,b	0.001
HCY, μmol/L	14.24 ± 6.73	13.33 ± 8.24	14.82 ± 8.77	0.442
HDL-C, mmol/L	1.09 ± 0.30	1.11 ± 0.29	1.08 ± 0.25	0.792
LDL-C, mmol/L	2.69 ± 0.98	2.95 ± 1.06	3.54 ± 1.36a,b	< 0.001
ApoA1, g/L	1.05 ± 0.21	1.11 ± 0.62	1.06 ± 0.21	0.730
ApoB, g/L	0.79 ± 0.28	0.86 ± 0.36	1.00 ± 0.33a,b	0.009
LP(a), mg/L	214.55 ± 290.31	275.79 ± 321.48	259.50 ± 331.44	0.517
ApoE, mg/L	46.69 ± 15.84	39.86 ± 14.11	45.43 ± 26.79	0.013

^aP < 0.05 vs E3 group.

^bP < 0.05 vs E2 group.

E2: Ε2/ε2 plus ε2/ε3; E3: Ε3/ε3; E4: Ε3/ε4 plus ε4/ε4. TG: Triglycerides; TC: Total cholesterol; HCY: Homocysteine; HDL-C: High-density lipoprotein cholesterol; LDL-C: Low-density lipoprotein cholesterol; ApoA1: Apolipoprotein A1; ApoB: Apolipoprotein B; ApoE: Apolipoprotein E; Lp(a): Lipoprotein(a).