©The Author(s) 2025.
World J Cardiol. Sep 26, 2025; 17(9): 110278
Published online Sep 26, 2025. doi: 10.4330/wjc.v17.i9.110278
Published online Sep 26, 2025. doi: 10.4330/wjc.v17.i9.110278
Table 3 Genotypes and alleles distribution of SLCO1B1 gene in the coronary heart disease group and control groups, n (%)
| Genotype | CHD group (n = 324) | Control group (n = 143) | Total (n = 467) | P value |
| *1a/*1a | 26 (8.02) | 11 (7.69) | 37 (7.92) | 0.902 |
| *1a/*1b | 104 (32.10) | 45 (31.47) | 149 (31.91) | 0.893 |
| *1b/*1b | 119 (36.72) | 61 (42.66) | 180 (38.54) | 0.225 |
| *1a/*5 | 1 (0.31) | 1 (0.70) | 2 (0.43) | 0.519 |
| *1a/*15 | 16 (4.94) | 5 (3.50) | 21 (4.50) | 0.488 |
| *1b/*15 | 55 (16.98) | 20 (13.99) | 75 (16.06) | 0.417 |
| *5/*5 | 0 (0) | 0 (0) | 0 (0) | NA |
| *5/*15 | 0 (0) | 0 (0) | 0 (0) | NA |
| *15/*15 | 3 (0.93) | 0 (0) | 3 (0.64) | 0.556 |
| Allele | CHD group (n = 648) | Control group (n = 286) | Total (n = 934) | |
| *1a | 173 (26.69) | 73 (25.52) | 246 (26.34) | 0.640 |
| *1b | 397 (61.17) | 187 (65.38) | 584 (62.53) | 0.231 |
| *5 | 1 (0.15) | 1 (0.35) | 2 (0.21) | 0.520 |
| *15 | 77 (11.83) | 25 (8.74) | 102 (10.92) | 0.156 |
- Citation: Xu JX, Wu Y, Zhang L, Wu YH, Li CL, Lin F. Correlation of APOE, SLCO1B1 and LPA KIV-2 gene polymorphisms with coronary heart disease in the Teochew population. World J Cardiol 2025; 17(9): 110278
- URL: https://www.wjgnet.com/1949-8462/full/v17/i9/110278.htm
- DOI: https://dx.doi.org/10.4330/wjc.v17.i9.110278