©The Author(s) 2025.
World J Cardiol. Sep 26, 2025; 17(9): 110278
Published online Sep 26, 2025. doi: 10.4330/wjc.v17.i9.110278
Published online Sep 26, 2025. doi: 10.4330/wjc.v17.i9.110278
Table 2 Genotypes and alleles distribution of APOE gene in the coronary heart disease group and control group, n (%)
| Genotype | CHD group (n = 324) | Control group (n = 143) | Total (n = 467) | P value |
| ε2/ε2 | 6 (1.85) | 2 (1.40) | 8 (1.71) | 1.000 |
| ε2/ε3 | 36 (11.11) | 31 (21.68) | 67 (14.35) | 0.003 |
| ε2/ε4 | 4 (1.23) | 3 (2.10) | 7 (1.50) | 0.442 |
| ε3/ε3 | 226 (69.75) | 90 (62.94) | 316 (67.67) | 0.147 |
| ε3/ε4 | 49 (15.12) | 16 (11.19) | 65 (13.92) | 0.258 |
| ε4/ε4 | 3 (0.93) | 1 (0.70) | 4 (0.86) | 1.000 |
| Allele | CHD group (n = 648) | Control group (n = 286) | Total (n = 934) | |
| ε2 | 52 (8.02) | 38 (13.29) | 90 (9.64) | 0.012 |
| ε3 | 537 (82.87) | 227 (79.37) | 764 (81.80) | 0.201 |
| ε4 | 59 (9.10) | 21 (7.34) | 80 (8.57) | 0.375 |
- Citation: Xu JX, Wu Y, Zhang L, Wu YH, Li CL, Lin F. Correlation of APOE, SLCO1B1 and LPA KIV-2 gene polymorphisms with coronary heart disease in the Teochew population. World J Cardiol 2025; 17(9): 110278
- URL: https://www.wjgnet.com/1949-8462/full/v17/i9/110278.htm
- DOI: https://dx.doi.org/10.4330/wjc.v17.i9.110278