Correlation of APOE, SLCO1B1 and LPA KIV-2 gene polymorphisms with coronary heart disease in the Teochew population

Table 1 Comparison of clinical characteristics between the coronary heart disease and control groups, n (%)

	CHD group (n = 324)	Control group (n = 143)	P value
Clinical data
Male	239 (73.77)	78 (54.55)	< 0.001
Age, years	64.93 ± 11.58	57.27 ± 13.74	< 0.001
BMI, kg/m2	23.21 ± 3.06	23.56 ± 3.89	0.746
Comorbidities
Hypertension	187 (57.72)	43 (30.07)	< 0.001
Diabetes	104 (32.10)	15 (10.49)	< 0.001
History of smoking	114 (35.19)	27 (18.88)	< 0.001
History of drinking	21 (6.48)	5 (3.50)	0.273
Laboratory data
TG, mmol/L	1.40 (0.89)	1.26 (0.72)	0.024
TC, mmol/L	4.69 (1.63)	4.87 (1.40)	0.580
HCY, μmol/L	11.87 (5.93)	9.82 (3.04)	< 0.001
HDL-C, mmol/L	1.07 (0.37)	1.19 (0.40)	< 0.001
LDL-C, mmol/L	2.95 (1.42)	2.87 (1.17)	0.422
ApoA1, g/L	1.05 (0.25)	1.16 (0.30)	< 0.001
ApoB, g/L	0.85 (0.35)	0.83 (0.30)	0.298
Lp(a), mg/L	122.50 (266.13)	100.2 (168.00)	0.007
ApoE, mg/L	38.65 (14.40)	38.95 (15.00)	0.627

BMI: Body mass index; TG: Triglycerides; TC: Total cholesterol; HCY: Homocysteine; HDL-C: High-density lipoprotein cholesterol; LDL-C: Low-density lipoprotein cholesterol; ApoA1: Apolipoprotein A1; ApoB: Apolipoprotein B; ApoE: Apolipoprotein E; Lp(a): Lipoprotein(a); CHD: Coronary heart disease.