Prevalence and impact of metabolically healthy obesity on cardiovascular outcomes in postmenopausal women and disparities: An age-matched study

Table 3 Independent predictors of major adverse cardiac and cerebral-vascular events in postmenopausal women with metabolically healthy obesity

Predictors	Odds ratio	95%CI	P value
Median household income national quartile for zip code			< 0.001
1 vs 4	1.29	1.11-1.50
2 vs 4	1.21	1.04-1.40
3 vs 4	0.96	0.83-1.12
Race			0.116
Black vs white	1.14	0.99-1.31
Hispanic vs white	0.90	0.75-1.08
Asian/PI vs white	0.96	0.57-1.59
Native American vs white	1.37	0.84-2.23
Payer type			0.074
Medicaid vs Medicare	0.93	0.78-1.10
Private vs Medicare	0.87	0.76-0.99
Self-pay vs Medicare	0.70	0.52-0.95
No charge vs Medicare	1.22	0.48-3.11
Elective admission, non-elective vs elective	7.38	5.91-9.22	< 0.001
Weekend admission, Saturday/Sunday vs Monday-Friday	1.05	0.94-1.17	0.392
Hospital location and teaching status			< 0.001
Urban non-teaching vs rural	1.12	0.91-1.38
Urban teaching vs rural	1.44	1.20-1.72
Hospital region			< 0.001
Midwest vs northeast	0.68	0.58-0.81
South vs northeast	0.94	0.80-1.09
West vs northeast	0.99	0.84-1.17
Peripheral vascular disease	1.16	0.95-1.42	0.156
Prior MI	1.39	1.05-1.85	0.021
Prior PCI	1.39	0.52-3.74	0.509
Prior CABG	1.34	0.86-2.06	0.193
Prior TIA	0.52	0.39-0.71	< 0.001
Prior VTE	0.65	0.53-0.79	< 0.001
Chronic kidney disease	0.95	0.83-1.09	0.489
Acquired immunodeficiency syndrome	0.80	0.29-2.24	0.673
Alcohol abuse	0.95	0.70-1.29	0.737
Drug abuse	1.09	0.83-1.42	0.548
Chronic pulmonary disease	1.09	0.98-1.20	0.121
Hypothyroidism	0.72	0.64-0.81	< 0.001
Other thyroid disorders	1.02	0.72-1.44	0.904
Valvular disease	1.27	0.84-1.91	0.258
Autoimmune condition	0.95	0.78-1.15	0.574
Dementia	1.19	0.97-1.46	0.092
Obstructive sleep apnea	0.72	0.62-0.85	< 0.001
Prior breast cancer	0.70	0.54-0.90	0.006
Anxiety disorders	0.78	0.68-0.90	0.001
Psychoses	0.50	0.34-0.73	< 0.001
Bariatric surgery status	0.54	0.40-0.72	< 0.001
Tobacco use disorders	0.63	0.56-0.71	< 0.001
Depression	0.81	0.70-0.94	0.004
Age (at admission)	1.02	1.02-1.03	< 0.001

P < 0.05 indicates statistical significance. Multivariable regression models were adjusted for age at admission, median household income, race, payer type, elective and weekend admission, hospital location and teaching status, peripheral vascular disease, tobacco use disorder, alcohol abuse, drug abuse, cancer, chronic kidney disease, prior myocardial infarction, prior primary coronary intervention, prior coronary artery bypass graft, heart failure, prior venous thromboembolism, prior transient ischemic attack/stroke, acquired immunodeficiency syndrome, depression, chronic pulmonary disease, hypothyroidism, other thyroid disorders, valvular disease, auto-immune conditions, obstructive sleep apnea, coronavirus disease 2019, prior bariatric surgery, prior breast cancer, anxiety disorders, psychoses, dementia, prior cancer. CI: Confidence intervals; MI: Myocardial infarction; PCI: Primary coronary intervention; VTE: Venous thromboembolism; TIA: Transient ischemic attack; CABG: Coronary artery bypass graft.