Comparison of beta-blockers vs calcium channel blockers in heart failure with preserved ejection fraction

Table 3 Balance of baseline characteristics after propensity score matching, mean (SD)

Variable	BB group (0) (n = 1733)	CCB group (1) (n = 1733)	SMD
Demographics
Age	70.25 (9.70)	70.26 (9.70)	0.001
Sex (male)	0.40 (0.49)	0.37 (0.48)	0.059
BMI	27.93 (5.17)	27.96 (5.19)	0.006
Smoking (%)			0.037
Current	417 (22.8)	391 (21.4)
Former	519 (28.4)	518 (28.4)
Never	890 (48.7)	917 (50.2)
Comorbidities
Hypertension	0.79 (0.40)	0.79 (0.41)	0.001
Diabetes	0.35 (0.48)	0.36 (0.48)	0.026
Coronary artery disease	0.27 (0.44)	0.27 (0.44)	0.002
Atrial fibrillation	0.23 (0.42)	0.23 (0.42)	0.005
Chronic kidney disease	0.20 (0.40)	0.21 (0.41)	0.035
COPD	0.14 (0.35)	0.15 (0.36)	0.03
Dyslipidemia	0.60 (0.49)	0.58 (0.49)	0.039
Clinical/Echo/Lab
Heart rate	75.47 (14.34)	74.83 (14.71)	0.044
SBP	130.33 (19.67)	129.94 (19.80)	0.02
DBP	74.59 (10.55)	74.40 (9.75)	0.018
NYHA class (%)			0.014
I (1)	201 (11.0)	201 (11.0)
II (2)	685 (37.5)	675 (37.0)
III (3)	745 (40.8)	757 (41.5)
IV (4)	195 (10.7)	193 (10.6)
LVEF	55.12 (4.83)	55.03 (5.03)	0.018
LAVI	40.61 (9.59)	39.86 (10.28)	0.076
E/e' ratio	12.12 (4.15)	12.12 (3.91)	0.001
RVSP	34.69 (10.33)	35.09 (10.13)	0.038
Creatinine	1.22 (0.51)	1.21 (0.49)	0.006
eGFR	59.80 (20.28)	59.25 (19.67)	0.028
BNP	561.34 (454.66)	561.68 (524.02)	0.001
Hemoglobin	13.05 (2.11)	13.08 (1.90)	0.013

BMI: Body mass index; COPD: Chronic obstructive pulmonary disease; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; NYHA: New York Heart Association; LVEF: Left ventricular ejection fraction; LAVI: Left atrial volume index; RVSP: Right ventricular systolic pressure; eGFR: Estimated glomerular filtration rate; BNP: B-type natriuretic peptide; BB: Beta-blockers; CCB: Calcium channel blockers.