Dual versus single antiplatelet therapy after lower extremity revascularization in peripheral artery disease: A systematic review and meta-analysis

Table 2 Baseline characteristics of patients in included studies comparing dual antiplatelet therapy and single antiplatelet therapy in peripheral artery disease

Ref.	Age (mean ± SD)		Current smoking		Type 2 diabetes mellitus		Hypertension		Hyperlipidemia/dyslipidemia		Coronary artery disease		Cerebrovascular disease (intracranial hemorrhage)		Chronic kidney disease/dialysis		Ankle-brachial index (mean)
	DAPT	SAPT	DAPT	SAPT	DAPT	SAPT	DAPT	SAPT	DAPT	SAPT	DAPT	SAPT	DAPT	SAPT	DAPT	SAPT	DAPT	SAPT
Rodriguez Alvarez et al[9], 2025	70	66	11	6	35	24	6	8	53	32	29	19	12	7	6	6	N/A	N/A
Armstrong et al[21], 2015	67	67	265	212	187	126	299	236	N/A	N/A	195	126	N/A	N/A	N/A	N/A	0.51	0.53
Belch et al[18], 2010	66.5	65.6	38.8	36.4	37.4	38	70.1	70	50.4	48.8	38.4	31	N/A	N/A	N/A	N/A	0.44	0.46
Belkini et al[26], 2020	65.8	66.4	42.6	42	51.1	45.2	90.1	85.1	N/A	N/A	35.1	25.4	N/A	N/A	3.8	3.7	N/A	N/A
Chinai et al[24], 2020	N/A	N/A	N/A	N/A	71	222	97	303	N/A	N/A	N/A	N/A	25	55	N/A	N/A	N/A	N/A
Cho et al[5], 2019	68.6	70.5	181	198	177	274	224	309	141	163	176	184	N/A	N/A			N/A	N/A
Ipema et al[25], 2020	68.7	74.4	75	99	40	68	58	98	61	65	N/A	N/A	N/A	N/A	3	5	N/A	N/A
Scheinert et al[19], 2012	68.6	70.5	34	21	24	32	12	23	N/A	N/A	12	34	N/A	N/A	21	11	0.52	0.47
Soden et al[22], 2016	68.1	67.8	37.1	38.2	45.2	44.8	87.9	88.5	N/A	N/A	31.1	30.5	N/A	N/A	6.4	5.9	N/A	N/A
Strobl et al[20], 2013	69.8	70.2	15	17	12	18	31	31	25	25	11	15	6	9	N/A	N/A	0.61	0.61
Thott et al[23], 2017	78	80	303	590	603	242	1054	488	N/A	N/A	N/A	N/A	59	169	133	49	N/A	N/A
Yamada et al[13], 2024	73.8	75.6	30	38	96	90	136	127	104	93	13	20	3	4	44	51	N/A	N/A

DAPT: Dual antiplatelet therapy; N/A: Not applicable; RCT: Randomized controlled trial; SAPT: Single antiplatelet therapy.