Frailty status and outcomes of percutaneous coronary intervention in elderly patients with non-ST-elevation myocardial infarction

Table 3 Independent predictors of in-hospital mortality by frailty category and percutaneous coronary intervention status

Variable	Low frailty	Intermediate frailty	High frailty	Interaction
	OR (95%CI, P value)	OR (95%CI, P value)	OR (95%CI, P value)	OR (95%CI, P value)
Intermediate vs low frailty without PCI	-	-	-	4.72 (4.39-5.08), 0.001
High vs low frailty without PCI	-	-	-	7.71 (7.09-8.39), 0.001
PCI effect in intermediate vs low frailty	-	-	-	1.56 (1.27-1.93), 0.001
PCI effect in high vs low frailty	-	-	-	1.83 (1.37-2.44), 0.001
Age	1.07 (1.06-1.08), < 0.001	1.01 (1.01-1.02), 0.001	1.00 (0.99-1.01), 0.918	1.02 (1.01-1.02), 0.001
Female (vs male)	0.93 (0.82-1.07), 0.310	0.78 (0.74-0.83), 0.001	0.82 (0.74-0.90), 0.001	0.81 (0.77-0.84), 0.001
Race ref: White
Black	0.93 (0.72-1.19), 0.556	0.94 (0.84-1.04), 0.201	1.18 (1.01-1.38), 0.032	0.99 (0.91-1.07), 0.804
Hispanic	0.85 (0.66-1.09), 0.202	0.91 (0.82-1.01), 0.066	0.93 (0.79-1.10), 0.389	0.90 (0.83-0.98), 0.017
Asian/Pacific Islander	1.05 (0.71-1.55), 0.801	1.14 (1.00-1.30), 0.052	1.21 (0.97-1.51), 0.085	1.15 (1.03-1.29), 0.013
Native American	0.49 (0.12-2.03), 0.327	1.09 (0.71-1.68), 0.691	1.29 (0.54-3.09), 0.572	1.05 (0.72-1.52), 0.799
Race: Other	0.91 (0.59-1.39), 0.652	1.09 (0.92-1.29), 0.333	1.35 (1.03-1.75), 0.028	1.13 (0.98-1.29), 0.084
Income quartile ref: USD 47999 (Q1)
USD 48000-USD 60999 (Q2)	0.91 (0.77-1.08), 0.286	0.86 (0.80-0.92), 0.001	1.00 (0.88-1.14), 0.974	0.89 (0.84-0.94), 0.001
USD 61000-81999 (Q3)	0.83 (0.69-1.00), 0.055	0.84 (0.78-0.91), 0.001	0.94 (0.82-1.08), 0.365	0.86 (0.81-0.91), 0.001
≥ USD 82000 (Q4)	0.75 (0.61-0.92), 0.007	0.83 (0.76-0.91), 0.001	0.90 (0.78-1.04), 0.161	0.84 (0.78-0.90), 0.001
Hospital region ref: Northeast
Midwest	1.03 (0.83-1.26), 0.809	0.85 (0.78-0.93), 0.001	0.74 (0.63-0.87), 0.001	0.85 (0.79-0.91), 0.001
South	1.12 (0.93-1.34), 0.242	0.89 (0.82-0.97), 0.005	0.69 (0.60-0.80), 0.001	0.87 (0.81-0.93), 0.001
West	1.15 (0.93-1.43), 0.190	1.00 (0.91-1.09), 0.973	0.90 (0.76-1.05), 0.183	0.99 (0.92-1.07), 0.841
Hospital location Ref: Non-teaching
Teaching	0.97 (0.88-1.07), 0.531	1.04 (0.99-1.08), 0.107	1.04 (0.96-1.12), 0.384	1.03 (0.99-1.06), 0.153
Hospital bed size ref: Small
Medium	1.07 (0.90-1.26), 0.443	1.15 (1.06-1.24), 0.001	1.05 (0.93-1.19), 0.449	1.12 (1.05-1.19), 0.001
Large	0.90 (0.77-1.06), 0.215	1.18 (1.10-1.27), 0.001	1.13 (1.00-1.28), 0.049	1.13 (1.07-1.20), 0.001
Charlson comorbidity index Ref: 1
2	1.25 (1.00-1.56), 0.046	1.12 (0.97-1.29), 0.123	0.97 (0.72-1.31), 0.856	1.15 (1.03-1.28), 0.011
3	1.28 (1.05-1.55), 0.013	0.97 (0.85-1.10), 0.621	0.84 (0.65-1.10), 0.209	1.02 (0.93-1.13), 0.679

P < 0.05 is considered statistically significant.

PCI: Percutaneous coronary intervention.