Do changes in intracoronary pressure aid coronary spasm diagnosis using the spasm provocation test?

Table 1 Patients’ characteristics

	Non-VSA	VSA	P value
n (%)	17 (24)	53 (18)
Age (yr)	68 ± 10	68 ± 9	0.775
Male/Female	3/14	33/20	0.001
Body mass index	24.4 ± 4.1	24.5 ± 3.8	0.914
Coronary risk factors (%)
Smoking (active/former/never)	2/2/13	11/16/26	0.134
Hypertension	14 (82)	39 (74)	0.463
Dyslipidemia	11 (65)	32 (60)	0.750
Diabetes mellitus	4 (24)	18 (34)	0.420
Alcohol consumer (%)	10 (13)	5 (29)	0.09
Family history of CAD (%)	4 (24)	14 (26)	0.813
CKD (%)	7 (41)	17 (32)	0.492
LVEF on UCG (%)	69 ± 7	66 ± 9	0.200
Brachial artery ultrasonography (n)	14	48
Brachial artery diameter at baseline (mm)	3.8 ± 0.8	3.9 ± 0.7	0.711
FMD (%)	6.2 ± 4.8	3.0 ± 3.6	0.008
NID (%)	17.7 ± 7.7	13.6 ± 6.9	0.061
Medications
Any kind of coronary vasodilator (%)	13 (76)	23 (43)	0.018
No. of coronary vasodilators	1 (0.5, 1)	0 (0, 1)	0.059
Beta-receptor blockers (%)	1 (6)	4 (8)	0.817
RAS inhibitors (%)	7 (41)	12 (23)	0.135
Lipid-lowering drugs (%)	4 (41)	17 (32)	0.492
Anti-platelet drugs (%)	4 (24)	18 (34)	0.420

CAD: Coronary artery disease; CKD: Chronic kidney disease; FMD: Flow-mediated dilation; LVEF: Left ventricular ejection fraction; NID: Nitroglycerin-induced dilation; RAS: Renin-angiotensin system; UCG: Cardiac ultrasonography; VSA: Vasospastic angina.