Right ventricle dysfunction does not predict mortality in patients with SARS-CoV-2-related acute respiratory distress syndrome on extracorporeal membrane oxygenation support

doi:10.4330/wjc.v15.i4.165

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 15, Issue 4

This Article

(135)

(164)

(0)

(9)

(3509)

(4)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Cardiology

ISSN

1949-8462

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

- Full Article with Cover (PDF)
- Full Article (XML)

Observational Study

World J Cardiol. Apr 26, 2023; 15(4): 165-173
Published online Apr 26, 2023. doi: 10.4330/wjc.v15.i4.165

Table 1 Comparison between patients with right ventricle dilatation and dysfunction and those without, n %

Variable	All patients	RVDD (No. 34)	No RVDD (No. 27)	P value
Clinical data
Age (yr), mean ± SD	54.3 ± 10.3	53.8 ± 9.7	52.9 ± 11	0.735
Gender, M/F	45/16 (74/26)	28/6 (82/18)	17/10 (63/37)	0.087
BMI (kg/m²), mean ± SD	32.9 ± 5.3	32.4 ± 5.6	32.7 ± 4.9	0.836
Charlson index, median (IQR)	2.0 (1.0-3.0)	2.0 (1.0-3.0)	2.0 (1.0-3.0)	0.772
Transferred from peripheral hospitals	38 (62)	18 (52)	20 (74)	0.9
Time from symptoms’ onset to ICU (d), median (IQR)	13 (10-13)	9 (8-12)	12 (10-14)	0.075
SOFA, median (IQR)	8.0 (7.0-10.0)	10 (8-10)	7 (6-10)	0.029
Mechanical ventilation length to ECMO support (d), median (IQR)	6.0 (8.0-11.0)	8.5 (6-12)	7 (4-10)	0.046
ECMO duration (d), median (IQR)	22 (13-42)	24.5 (9-44)	21 (15-35)	0.765
Renal replacement therapy	29 (48)	22 (65)	7 (26)	0.002
ICU death	33 (54.1)	21 (62)	12 (44)	0.024
Biohumoral data
Creatinine (mg/dL), median (IQR)	1.00 (0.72-1.86)	0.83 (0.61-1.34)	1.65 (0.78-2.00)	0.025
D-dimer (ng/mL), median (IQR)	3594 (2252-7214)	3748 (1740-12085)	3550 (2368-5007)	0.425
CRP (mg/dL), median (IQR)	142 (88-144)	121 (87-174)	165 (98-212)	0.55
IL-6 (pg/mL), median (IQR)	34 (7.4-70.0)	45 (6.9-105.0)	34 (21-58.0)	0.772
Troponin (pg/mL), median (IQR)	21 (14.0-38.0)	33.0 (14.0-112.0)	21.0 (8.5-48.0)	0.253
NT-pro BNP (pg/mL), median (IQR)	874 (345-1654)	735 (252-1467)	1273 (585-1868)	0.058
LDH IU/L, median (IQR)	465 (375-538)	421 (363-510)	473 (424-542)	0.078
Echocardiographic data
LVEF (%), mean ± SD	63.9 ± 7.6	64.3 ± 7.9	64.5 ± 7.5	0.113
RV/LV, mean ± SD	0.58 ± 0.17	0.69 ± 0.08	0.45 ± 0.14	0.0001
TAPSE (mm), mean ± SD	18.0 (10.0-21.0)	13.9 (10.0 ± 14.5)	17.4 (16.0-22.5)	0.015
sPAP (mmHg), mean ± SD	58.4 ± 9.4	64 ± 11	59.1 ± 7.7	0.015
e/e1	11 ± 3	12 ± 3	9 ± 3	0.0003
TAPSE/sPAP (mm/mmHg), mean ± SD	0.28 ± 0.13	0.19 ± 0.10	0.28 ± 0.11	0.001
Ventilatory parameters
PEEP (cm H₂O), mean ± SD	12.2 ± 2.3	12.4 ± -2.4	12.1 ± 2.6	0.64
PO₂/FiO₂, mean ± SD	62 (50-88)	66 (54-88)	60 (50-88)	0.442
Norepinephrine, mean ± SD	0.34 ± 0.22	0.39 ± 0.26	0.24 ± 0.10	0.011

IQR: Interquartile range; RVDD: Right ventricle dilatation and dysfunction; BMI: Body mass index; ICU: Intensive care unit; LOS: Length of stay; CRP: C-reactive protein; IL-6: Interleukin 6, SOFA: Simplified organ functional assessment; ECMO: Extracorporeal membrane oxygenation; NT pro BNP: N terminal pro brain natriuretic peptide; RV: Right ventricle; LV: Left ventricle; EF: Ejection fraction; TAPSE: Tricuspid annular plane systolic excursion; sPAP: Systolic pulmonary arterial pressure; LDH: Lactate dehydrogenase; LVEF: Left ventricular ejection fraction; PEEP: Positive end-expiratory pressure.

Full Size Table

Citation: Lazzeri C, Bonizzoli M, Batacchi S, Cianchi G, Franci A, Socci F, Chiostri M, Peris A. Right ventricle dysfunction does not predict mortality in patients with SARS-CoV-2-related acute respiratory distress syndrome on extracorporeal membrane oxygenation support. World J Cardiol 2023; 15(4): 165-173
URL: https://www.wjgnet.com/1949-8462/full/v15/i4/165.htm
DOI: https://dx.doi.org/10.4330/wjc.v15.i4.165

Lazzeri C, Bonizzoli M, Batacchi S, Cianchi G, Franci A, Socci F, Chiostri M, Peris A. Right ventricle dysfunction does not predict mortality in patients with SARS-CoV-2-related acute respiratory distress syndrome on extracorporeal membrane oxygenation support. World J Cardiol 2023; 15(4): 165-173 [PMID: 37124973 DOI: 10.4330/wjc.v15.i4.165]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.