Role of fibrinogen, albumin and fibrinogen to albumin ratio in determining angiographic severity and outcomes in acute coronary syndrome

Table 2 Comparison between patients with total occlusion of culprit artery compared to patients with > thrombolysis in myocardial infarction 2 flow

	Patients with TIMI- ≤ 1 flow (n = 54)	Patients with TIMI- ≥ 2 flow (n = 98)	P value
Age, yr	60.5 ± 10.2	60.5 ± 10.7	0.9
Time of presentation to hospital after chest pain onset (h)	13.4 ± 11.2	12.3 ± 8.8	0.24
Hypertension	33 (61)	71 (65)	0.3
Active smokers	16 (29.6)	36 (32.4)	0.3
EF < 30%	23 (42.6)	33 (29.7)	0.1
Cardiogenic shock	10 (18.5)	15 (13.5)	0.4
Complete heart block	8 (14.8)	7 (6.3)	0.07
Time to initiation of medical treatment, h	77.3 ± 63	74.5 ± 66	0.87
Time to angiography, h	107 ± 79	113 ± 141	0.84
CK-MB	101.2 ± 90	75 ± 83.4	0.11
Platelet (× 109/L)	1.89 ± 0.7	2.0 ± 0.91	0.17
Procalcitonin (ng/mL)	0.59 ± 0.7	1.0 ± 2.6	0.27
TLC (× 109/L)	10.6 ± 3.8	10.7 ± 3.9	0.8
CRP (mg/dL)	47.2 ± 34.3	39.7 ± 28.4	0.16
Fibrinogen (gm/L)	6.9 ± 1.04	5.4 ± 1.2	0.001
Albumin (gm/dL)	3.3 ± 0.35	3.4 ± 0.32	0.014
FAR	21.1 ± 3.9	15.6 ± 4.1	0.001

EF: Ejection fraction; CK-MB: Creatinine kinase; TLC: Total leukocyte count; FAR: Fibrinogen to albumin ratio; CRP: C-reactive protein; TIMI: Thrombolysis in myocardial infarction.