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Copyright ©The Author(s) 2020.
World J Cardiol. Jun 26, 2020; 12(6): 248-261
Published online Jun 26, 2020. doi: 10.4330/wjc.v12.i6.248
Table 2 International Takotsubo Diagnostic Criteria (InterTAK Diagnostic Criteria)[8]
No.International Takotsubo Diagnostic Criteria
1Transient left ventricular dysfunction (hypokinesia, akinesia, dyskinesia), manifests as apical ballooning or mid-ventricular, basal or focal wall motion abnormality, which usually extend beyond a single epicardial vascular distribution. Right ventricular involvement can be present
2A mental, physical or mixed cause can precede the event of Takotsubo syndrome but this is not necessary
3Takotsubo syndrome can be caused by neurological conditions (e.g. subarachnoid hemorrhage, stroke/transient ischemic attack, or seizures) as well as pheochromocytoma
4Electrocardiogram changes (elevation or depression of the ST-segment, inversion of the T-wave and prolongation of the QTc); however, there are unusual cases without electrocardiogram changes
5Elevation of cardiac biomarkers (troponin and creatine kinase)
6Significant coronary artery disease could also be present in Takotsubo syndrome
7Exclusion of acute myocarditis, in this case cardiovascular magnetic resonance is recommended
8The pathology is common in postmenopausal women are predominantly affected