Impact of gout on in-hospital outcomes of acute coronary syndrome-related hospitalizations and revascularizations: Insights from the national inpatient sample

doi:10.4330/wjc.v11.i5.137

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World Journal of Cardiology

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1949-8462

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Cardiol. May 26, 2019; 11(5): 137-148
Published online May 26, 2019. doi: 10.4330/wjc.v11.i5.137

Table 5 Predictors of in-hospital mortality in acute coronary syndrome patients with gout undergoing revascularization

Predictor	Adjusted odds ratio	95%CI (LL-UL)	P value
Age in years at admission			< 0.001^a
45-64 vs 18-44	2.99	1.08-8.30	0.036^a
65-84 vs 18-44	5.72	2.04-16.01	0.001^a
≥ 85 vs 18-44	15.63	5.51-44.39	< 0.001^a
Male vs female	0.89	0.75-1.05	0.155
Race			< 0.001^a
African American vs white	1.09	0.88-1.35	0.413
Hispanic vs white	0.45	0.31-0.67	< 0.001^a
Asian vs white	0.65	0.45-0.94	0.022^a
Non-elective vs elective admission	2.00	1.44-2.79	< 0.001^a
Median household income quartile 0-25^thvs 76-100^th#	1.44	1.17-1.78	0.001^a
Comorbidities
Alcohol abuse	0.49	0.31-0.79	0.003^a
Rheumatoid arthritis/collagen vascular diseases	1.57	1.09-2.25	0.016^a
Congestive heart failure	5.91	3.54-9.86	0.000^a
Coagulopathy	1.29	1.05-1.58	0.014^a
Drug abuse	2.33	1.34-4.05	0.003^a
Fluid and electrolyte disorders	2.88	2.49-3.35	< 0.001^a
Other neurological disorders	1.72	1.33-2.23	< 0.001^a
Obesity	0.79	0.66-0.95	0.012^a
Peripheral vascular disorders	1.60	1.36-1.88	< 0.001^a
Renal failure	2.04	1.13-3.70	0.019^a
Valvular disease	8.15	3.87-17.15	< 0.001^a
Dyslipidemia	0.63	0.54-0.72	< 0.001^a
Outcomes/postoperative complications
Hypotension/shock	2.97	1.93-4.56	< 0.001^a
Cardiac complications	1.59	1.19-2.11	0.002^a
Postoperative myocardial infarction	2.53	1.74-3.68	< 0.001^a
Perioperative stroke	2.48	1.20-5.10	0.014^a
Respiratory complications	1.80	1.41-2.30	< 0.001^a
Postoperative acute kidney injury	1.48	1.26-1.74	< 0.001^a
Infections/septicemia	3.94	3.01-5.16	< 0.001^a

^aP < 0.05 indicates clinical significance. CI: Confidence interval; LL: Lower level; UL: Upper level, Multivariate regression model was adjusted for age, gender, race, admission type, median household income, payer status, hospital characteristics and all relevant comorbidities and prior medical history.

Citation: Desai R, Parekh T, Goyal H, Fong HK, Zalavadia D, Damarlapally N, Doshi R, Savani S, Kumar G, Sachdeva R. Impact of gout on in-hospital outcomes of acute coronary syndrome-related hospitalizations and revascularizations: Insights from the national inpatient sample. World J Cardiol 2019; 11(5): 137-148
URL: https://www.wjgnet.com/1949-8462/full/v11/i5/137.htm
DOI: https://dx.doi.org/10.4330/wjc.v11.i5.137