Challenges in the chemotherapy of Chagas disease: Looking for possibilities related to the differences and similarities between the parasite and host

doi:10.4331/wjbc.v8.i1.57

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Feb 26, 2017 (publication date) through Apr 25, 2024

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World Journal of Biological Chemistry

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1949-8454

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Biol Chem. Feb 26, 2017; 8(1): 57-80
Published online Feb 26, 2017. doi: 10.4331/wjbc.v8.i1.57

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Figure 11 Chemical structures of the first T. cruzi trans-sialidase inhibitors (14-18). The more potent is (18), with a Ki = 300 μmol/L.

Citation: Sueth-Santiago V, Decote-Ricardo D, Morrot A, Freire-de-Lima CG, Lima MEF. Challenges in the chemotherapy of Chagas disease: Looking for possibilities related to the differences and similarities between the parasite and host. World J Biol Chem 2017; 8(1): 57-80
URL: https://www.wjgnet.com/1949-8454/full/v8/i1/57.htm
DOI: https://dx.doi.org/10.4331/wjbc.v8.i1.57