Review
Copyright ©The Author(s) 2017.
World J Biol Chem. Feb 26, 2017; 8(1): 57-80
Published online Feb 26, 2017. doi: 10.4331/wjbc.v8.i1.57
Figure 3
Figure 3 Benznidazole (1) is converted to nitroso metabolites and N-Aryl hydroxylamine, which can be enzymatically reduced to the corresponding 2-aminoimidazole derivative or nitrenio ion, which then is spontaneously di-hydroxylated generating a glyoxal molecule and guanidine derived.