Cathepsins mediate tumor metastasis

Table 2 Cathepsin family members expressed in cancers

Cathepsin	Elevated in cancer	Location of cancer
A	Yes	Malignant melanoma
B	Yes	Breast carcinomas, melanoma, gastric cancer, lung cancer, colon cancer, ovarian cancer, cervical cancer pancreatic carcinomas, glioblastoma thyroid carcinoma,cholangiocarcinomas, hepatocellular carcinomas, bladder caner
C	Unclear
D	Yes	Thyroid carcinomas, squamous cell carcinoma, renal cell, carcinoma, glioma brain tumors, laryngeal carcinoma, breast cancer, lung cancer, ovarian carcinoma
E	Yes	Pancreatic ductal adenocarcinoma, gastric cancer
F	Yes	cervical carcinoma
G	Yes	Breast cancer
H	Yes	Breast carcinoma, colorectal cancer, melanoma, head and neck carcinoma, glioma, prostate cancer
L	Yes	Breast cancer, lung cancer, gastric cancer, colon cancer, head and neck carcinomas, melanomas, gliomas, ovarian cancer, pancreatic cancer
K	Yes	Gastric cancer, squamous cell carcinoma, basal cell carcinoma, breast tumor, lung cancer, melanomas, prostate tumors, renal tumor
O	Unclear
S	Yes	Astrocytoma, gastric cancer, hepatocellular carcinomas, glioblastomas, melanoma, gastric cancer, pancreatic islet cell cancer
V	Unclear
W	Unclear
X	Yes	Prostate cancer, gastric cancer, malignant melanomas, prostate cancer, lung tumors, breast cancer, colonrectal cancer
Z	Yes	Melanomas, gastric cancer, hepatocellular carcinomas, pancreatic carcinomas