Methionine sulfoxide reductase A: Structure, function and role in ocular pathology

Figure 2 Immunohistochemical localization of αA-crystallin (red), αB-crystallin (red) and methionine sulfoxide reductase A (green) in the retina of patients with AMD. Retinal cryosections were air-dried, fixed, and processed as described[18] using αA-crystallin and αB-crystallin rabbit polyclonal antibodies (Stressgen, Ann Arbor, MI, USA), and mouse monoclonal methionine sulfoxide reductase (Msr) A antibody (Novus Biologicals, Littleton, CO, USA). Sections were viewed under a confocal microscope (Carl Zeiss, Thornwood, NY, USA). Arrows indicate co-localization (yellow) of αA-crystallin or αB-crystallin and MsrA. AMD:Age-related macular degeneration; *: Drusen; Scale bar = 50 μm.