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©2013 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Biol Chem. May 26, 2013; 4(2): 16-17
Published online May 26, 2013. doi: 10.4331/wjbc.v4.i2.16
Published online May 26, 2013. doi: 10.4331/wjbc.v4.i2.16
Heart and Brain: A neutro-genomic link
Vivek Priy Dave, Central Lab, R and D Center, Gangwon-do 200-883, South Korea
Deepak Kaul, Department of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India
Author contributions: All authors contributed equally to this work.
Correspondence to: Dr. Vivek Priy Dave, PhD, Central Lab, R and D Center, 1144-2G-Tech Geoduri, Dongnaemyeon, Chuncheon, Gangwon-do 200-883, South Korea. vivek_priy2000@yahoo.co.in
Telephone: +82-33-2431411 Fax: +82-33-2439373
Received: February 18, 2013
Revised: April 23, 2013
Accepted: April 28, 2013
Published online: May 26, 2013
Revised: April 23, 2013
Accepted: April 28, 2013
Published online: May 26, 2013
Core Tip
Core tip: The progression from a healthy phenotype to a chronic disease phenotype comes into existence by abnormal regulation of gene expression, influenced by the dietary components and gene environment interaction. Liver X Receptor-α is one of the key transcription factor which is modulated by the dietary components such as oxycholesterol, withaferin A, vitamin C, vitamin D and statins. Thus the molecule attracts its role in the field of neutro-genomics.