Quality of life in patients with chronic anal fissure after topical treatment with diltiazem

Table 3 Relationships between short-forum 36 health survey subscale and fissure symptoms: dependence on age, sex, co-morbidity, employment and duration of disease¹

Variabales included in equation	Unstandardized regression weight	t value	P value	Variabales explained
Physical functioning
Age (yr)	-0.49	-2.63	0.01	21%
Bodily pain
Pain2	-7.45	-5.24	< 0.0001	51%
Energy (vitalit)
Age (yr)	0.64	3.47	0.002	39%
Irritation2	-2.66	-2.14	0.04
Social functioning
Pain2	-3.83	-2.34	0.03	17%
Role emotional
Duration of disease (mo)	-0.18	-2.61	0.02	21%
Mental health
Irritation2	-2.94	-3.05	0.005	32%
Sex (males vs females)	12.90	2.11	0.04

¹A stepwise multiple regression analysis was used to establish which variables best predicted quality of life;

²Numeral Rating Scales before treatment. The Short-Forum 36 health survey subscales were selected for the dependent variables. The symptom scores of pain, bleeding, or irritation at baseline were independent vareiables. Age, sex, co-morbidity, employment, and duration of disease were analyzed as additional covariates.